Multiple Sclerosis Clinical Trial
Official title:
The Additional Effect of Intrapulmonary Percussive Ventilation (IPV) on Respiration in People With Multiple Sclerosis (MS).
This study aims to investigate whether intrapulmonary percussive ventilation (IPV) in combination with active breathing exercises using the flow-based incentive spirometer (Inspirix) has a positive effect on the respiratory values in people with multiple sclerosis (MS).
The primary research question includes "what is the additional effect of intensive IPV
treatment in combination with active breathing exercises on respiratory power (Peak
Expiratory Flow, PEF) in people with MS?".
In a single-center randomized clinical trial, 96 people with MS-related respiratory problems
will be allocated to either the intervention group (IPV + active breathing training) or the
control group (active breathing training only). Interventions will be provided by trained
speech- and language therapists, in combination with a multidisciplinary rehabilitation
programme of 3 weeks. Pre- en posttraining assessment includes measures of respiration,
speech and fatigue.
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