Multiple Sclerosis Clinical Trial
Official title:
Sexual Dysfunction in Patients With Relapsing Remitting Multiple Sclerosis and Associated Comorbidities
This work aims to:
1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis
patients with specific focus on
1. Specific neurologic deficit.
2. Depressive symptoms.
3. Comorbid factors.
4. Fatigue symptoms.
2. To investigate the impact of Sexual dysfunction on Sexual Quality of Life (SQoL).
3. To search for possible gender difference.
The present study is a cross sectional study on 120 MS adolescent patients meeting the
McDonald's criteria; 60 male cases and 60 female cases recruited from Mansoura University
Hospitals, Egypt.
All patients were subjected to the following:
1. Clinical Evaluation:
1. Thorough neurological examination.
2. Cognitive functions by Minimental State Examination (MMSE).
e. Expanded Disability Severity Scale (EDSS).
2. Neurophysiological Evaluation:
a. Visual Evoked Potential (VEP).
3. Imaging Evaluation:
a. Conventional MRI.
4. Cerebrospinal Fluid (CSF):
5. Sexual dysfunction measure: through the international index of erectile function (IIEF),
female sexual function questionnaire (SFQ) and the sexual Quality of life male and
female version (SQoL) (American Psychiatric Association, 1994).
6. Depressive symptoms assessment through The BDI (The Beck Depression Inventory) which is
the most common instrument measuring the severity of depression.
7. Fatigue symptoms were evaluated through fatigue subscale of Multiple Sclerosis Quality
of Life-54(MSQOL-54).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05528666 -
Risk Perception in Multiple Sclerosis
|
||
| Completed |
NCT03608527 -
Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis
|
N/A | |
| Recruiting |
NCT05532943 -
Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis
|
Phase 1/Phase 2 | |
| Completed |
NCT02486640 -
Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With Betaferon
|
||
| Completed |
NCT01324232 -
Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
|
Phase 2 | |
| Completed |
NCT04546698 -
5-HT7 Receptor Implication in Inflammatory Mechanisms in Multiple Sclerosis
|
||
| Active, not recruiting |
NCT04380220 -
Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
|
||
| Completed |
NCT02835677 -
Integrating Caregiver Support Into MS Care
|
N/A | |
| Completed |
NCT03686826 -
Feasibility and Reliability of Multimodal Evoked Potentials
|
||
| Recruiting |
NCT05964829 -
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
|
N/A | |
| Withdrawn |
NCT06021561 -
Orofacial Pain in Multiple Sclerosis
|
||
| Completed |
NCT03653585 -
Cortical Lesions in Patients With Multiple Sclerosis
|
||
| Recruiting |
NCT04798651 -
Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
|
N/A | |
| Active, not recruiting |
NCT05054140 -
Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis
|
Phase 2 | |
| Completed |
NCT05447143 -
Effect of Home Exercise Program on Various Parameters in Patients With Multiple Sclerosis
|
N/A | |
| Recruiting |
NCT06195644 -
Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients
|
Phase 1 | |
| Completed |
NCT04147052 -
iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple Sclerosis
|
N/A | |
| Completed |
NCT03591809 -
Combined Exercise Training in Patients With Multiple Sclerosis
|
N/A | |
| Completed |
NCT03594357 -
Cognitive Functions in Patients With Multiple Sclerosis
|
||
| Completed |
NCT02845635 -
MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis
|