Functional Electrical Stimulation Cycling for Managing Mobility Disability in People With Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title: Functional Electrical Stimulation Cycling for Managing Mobility Disability in People With Multiple Sclerosis

Status Recruiting

Clinical Trial Summary

Mobility impairment is one of the most common, poorly managed, and life altering consequences of MS. Current therapies for managing MS do not prevent the long-term accumulation of mobility impairment, highlighting the need for alternative strategies that prevent or slow progressive mobility disability. The proposed trial will test the efficacy and lasting effects of functional electrical stimulation (FES) cycling as an exercise-based rehabilitation strategy for managing mobility impairment and associated consequences in MS.

Clinical Trial Description

The study is an assessor-blinded RCT for examining the efficacy and lasting effects of 24 weeks of supervised FES cycling exercise compared to passive leg cycling on mobility and secondary outcomes in people with MS with mobility impairment. Participants who meet the eligibility criteria will undergo the informed consent process and baseline assessment. Participants will then be randomized to either the FES or passive leg cycling program. Following baseline assessment, participants will complete a 24-week leg cycling program, with a mid-point assessment at 12 weeks. At 24 weeks, participants will undergo a post-intervention assessment. Following a 12-week follow-up period, participants will undergo a final assessment. Each participant will be involved in the study for approximately 10 months. ;

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

• NCT number: NCT03949387
• Study type: Interventional
• Source: University of Ottawa
• Contact: Myriam Venasse
• Phone: (613) 562-5800
• Email: cepl@uottawa.ca
• Status: Recruiting
• Phase: N/A
• Start date: October 16, 2019
• Completion date: January 2025