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Clinical Trial Summary

The purpose of the study is to determine if lipoic acid can preserve mobility and protect the brain in progressive forms of multiple sclerosis.


Clinical Trial Description

This two-year study will determine if daily oral intake of lipoic acid will prove superior to placebo in reducing injury to the brain and maintaining mobility in progressive MS. Mobility will be assessed with the timed 25-foot walk test and 2-minute timed walk test as well as fall counts. Neuroprotection will be measured by the extent of brain volume loss seen on MRI. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03161028
Study type Interventional
Source VA Office of Research and Development
Contact
Status Active, not recruiting
Phase Phase 2
Start date July 1, 2018
Completion date June 30, 2024

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