Multiple Sclerosis Clinical Trial
Official title:
Effect of Video Game Based Physical Activity Training on Upper Extremity Functions, Walking, Balance and Cognitive Functions in Persons With Multiple Sclerosis
The study was designed to investigate the effect of video games based physical activity training on upper extremity functions, walking, balance and cognitive functions in persons with multiple sclerosis (MS). For this aim, the participants with MS will be divided into three groups: game based physical activity training, conventional rehabilitation, and no intervention groups. The experimental groups will receive therapy sessions once a week for 8 weeks. The no intervention group will receive no intervention, they will be assessed at baseline and after 8 weeks.
MS is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous
system. The most common clinical signs and symptoms are fatigue, spasticity, affecting
mobility, cognitive impairment, chronic pain, depression, decreased quality of life, and
bladder and bowel dysfunction.
In order to increase and maintain the quality of life of individuals with MS these
disease-related progressive symptoms need to be managed. For this reason, patients need
long-term rehabilitation. This situation reduces the motivation of the people over time and
makes the continuity of treatment difficult. Developments in rehabilitation technology aim to
contribute to the treatment process as well as to increase the active participation of
individuals with chronic diseases.
Current literature has shown that video-based physical activity training as
non-pharmacological therapy may be an effective method for symptoms such as balance, tremor,
fatigue, cognitive functions in persons with MS.
The primary purpose of the study was to examine the effects and persistence of 8-week video
games-based physical activity training in MS patients on upper extremity functions, walking,
balance, cognitive functions, quality of life, depression and fatigue. The second aim of the
study was to investigate the effect and persistence of traditional physiotherapy of 8 weeks
on MS patients on upper extremity functions, walking, balance, cognitive functions, quality
of life, depression and fatigue. The third aim of the study is to compare the effects of
8-week videogame-based physical activity training and traditional physiotherapy in MS
patients.
Volunteers from persons with MS who are in routine control of the MS Outpatient Clinic of
Neurology Department, Faculty of Medicine, Dokuz Eylül University will participate in the
study. In accordance with the inclusion criteria, 51 patients were randomly assigned to three
groups: 17 patients in the game based rehabilitation group, 17 patients in the conventional
rehabilitation group and 17 patients in the no intervention group. Based on the physical
levels of the patients, appropriate games will be selected and video game based physical
activity training will be started. Video games will be played with Xbox One with motion
sensor (Microsoft) and a 52'' Liquid Crystal Display. Depending on the prognosis of the
patients, the grades of the games and types of the games will be changed. The program will be
administered once a week for 8 weeks. A conventional physiotherapy program including balance,
upper extremity, and core stabilization exercises will be implemented. Sessions will take
5-10 minutes warm up, 15-20 minutes exercise and 5-10 minute cool down periods. The program
will be administered once a week for 8 weeks. No intervention group formed from waitlist will
receive no intervention.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05528666 -
Risk Perception in Multiple Sclerosis
|
||
Completed |
NCT03608527 -
Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis
|
N/A | |
Recruiting |
NCT05532943 -
Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis
|
Phase 1/Phase 2 | |
Completed |
NCT02486640 -
Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With Betaferon
|
||
Completed |
NCT01324232 -
Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
|
Phase 2 | |
Completed |
NCT04546698 -
5-HT7 Receptor Implication in Inflammatory Mechanisms in Multiple Sclerosis
|
||
Active, not recruiting |
NCT04380220 -
Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
|
||
Completed |
NCT02835677 -
Integrating Caregiver Support Into MS Care
|
N/A | |
Completed |
NCT03686826 -
Feasibility and Reliability of Multimodal Evoked Potentials
|
||
Recruiting |
NCT05964829 -
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
|
N/A | |
Withdrawn |
NCT06021561 -
Orofacial Pain in Multiple Sclerosis
|
||
Completed |
NCT03653585 -
Cortical Lesions in Patients With Multiple Sclerosis
|
||
Recruiting |
NCT04798651 -
Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
|
N/A | |
Active, not recruiting |
NCT05054140 -
Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis
|
Phase 2 | |
Completed |
NCT05447143 -
Effect of Home Exercise Program on Various Parameters in Patients With Multiple Sclerosis
|
N/A | |
Recruiting |
NCT06195644 -
Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients
|
Phase 1 | |
Completed |
NCT04147052 -
iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple Sclerosis
|
N/A | |
Completed |
NCT03594357 -
Cognitive Functions in Patients With Multiple Sclerosis
|
||
Completed |
NCT03591809 -
Combined Exercise Training in Patients With Multiple Sclerosis
|
N/A | |
Completed |
NCT02845635 -
MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis
|