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Clinical Trial Summary

The purpose of this expanded access retrospective study is to determine whether tetracyclines, statins and antimycotics are effective in improvement of life and health condition in the treatment of multiple sclerosis due to autoimmune disease (MS) in all his forms, specially in patients that show no response to commonly used treatments


Clinical Trial Description

The purpose of this expanded access retrospective study is to determine whether tetracyclines, statins and antimycotics are effective in improvement of life and health condition in the treatment of multiple sclerosis due to autoimmune disease (MS) in all his forms.

The method of analysis chosen was the analysis of movement through the analysis of the mobility with the Barthel Index (disability evaluation) before and after treatment, the analysis of muscle imbalance Kendall before and after treatment and the final EDSS score.The treatment had a total duration of 45 days with three active principles subministration for 2 times a day, controlled nutrition, physiotherapy and gymnastics.

Considering the above, therefore, seems promising, also because of the low toxicity of the active, non immunosuppressant action and indeed exciting and synergistic action between them in the interests of recovery of homeostasis of the organism, the conduct of a suitable observational trial aimed at demonstrating the ability anti inflammatory and potentially reconstruction of damaged tissues, specially in patients that show no response to commonly used treatments ;


Study Design

N/A


Related Conditions & MeSH terms

  • Autoimmune Diseases
  • Disseminated or Multiple Sclerosis Nos
  • Multiple Sclerosis
  • Multiple Sclerosis, Acute Relapsing
  • Multiple Sclerosis, Chronic Progressive
  • Multiple Sclerosis, Primary Progressive
  • Multiple Sclerosis, Relapsing-Remitting
  • Sclerosis

NCT number NCT02606929
Study type Expanded Access
Source Università Popolare Homo & Natura
Contact
Status Temporarily not available
Phase Phase 0
Start date January 2015
Completion date November 2015

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