Multiple Sclerosis Clinical Trial
Official title:
Stabilometric Assessment of Context Dependent Balance Recovery in Persons With Multiple Sclerosis: a Randomized Controlled Study
Background: Balance control relies on accurate perception of visual, somatosensory and
vestibular cues. Sensory flow is impaired in Multiple Sclerosis (MS) and little is known
about the ability of the sensory systems to adapt after neurological lesions reducing
sensory impairment. The aims of the present study were to verify whether:
1. Balance rehabilitation administered in a challenging sensory conditions would improve
stability in upright posture
2. the improvement in a treated sensory condition would transfer to a non treated sensory
condition.
Methods: Fifty three persons with Multiple Sclerosis, median (min-max) Expanded Disability
Status Scale score of 5 (2.5-6.5), participated in a Randomized Controlled Trial and were
randomly assigned to two groups. The Experimental group received balance rehabilitation
aimed at improving motor and sensory strategies. The Control group received rehabilitation
treatment which did not include training of sensory strategies. Persons with Multiple
Sclerosis were blindly assessed by means of a stabilometric platform with eyes open, eyes
closed and dome, on both firm surface and foam. Anterior-posterior and medio-lateral sway,
velocity of sway and the length of Center of Pressure (CoP) trajectory were calculated in
the six sensory conditions.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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