Consolidation & Interference in Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:

Consolidation & Interference in Multiple Sclerosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02081508
• Other study ID #: R-800-13
• Status: Completed
• Phase: N/A
• First received: March 5, 2014
• Last updated: July 28, 2016
• Start date: March 2014
• Est. completion date: May 2015

Study information

• Verified date: July 2016
• Source: Kessler Foundation
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The purpose of this research study is to investigate whether minimizing interference improves memory in multiple sclerosis.

Description:

The ability to form new long-lasting memories is important for successful independent living and a high quality of life. Roughly half of the individuals diagnosed with Multiple Sclerosis (MS) have difficulty remembering new information and this is likely associated with poor acquisition of new information. There are only a limited number of studies that have investigated memory consolidation in MS. The current study will investigate the role of interference during the consolidation time period of memory formation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 39
• Est. completion date: May 2015
• Est. primary completion date: May 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• If you are between the ages of 18-65.

• If you have a diagnosis of Multiple Sclerosis (MS) or are medically healthy.

• If you have MS, you have not had a flare up of MS symptoms in the past month.

• You do not have other neurological issues such as, Epilepsy or Stroke.

• You do not have a significant history of psychiatric problems or a current diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder .

• You do not have a significant history of drug or alcohol abuse.

• You can read and speak English fluently.

• You are not currently taking steroids.

Exclusion Criteria:

• You are younger than 18 years old.

• You are older than 65 years old.

• You have had a prior stroke or neurological disease other than MS.

• You have a history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis) or a current diagnosis of Major Depressive Disorder, Bipolar Disorder.

• You have a significant alcohol or drug abuse history.

• You are currently taking steroids.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

Intervention

Behavioral:
• Interference onset
Temporal duration of interference onset.

Locations

Country	Name	City	State
United States	Kessler Foundation	West Orange	New Jersey

Sponsors (1)

Lead Sponsor	Collaborator
Kessler Foundation

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Recall Proportion		2 hours	No