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A Pilot Study Assessing the Impact of Gilenya Therapy on Bone Density Change in Relapsing Forms of Multiple Sclerosis — MS-BMD  

Multiple Sclerosis Clinical Trial

Official title:
A Single Center Prospective, Open Label, Pilot Study to Assess Change in Bone Mass Density and Select Bone Turnover Biomarkers in Gilenya Treated Versus Non-Gilenya Treated Ambulatory Subjects With a Relapsing Form of Multiple Sclerosis

Clinical Trial Summary

The purpose of this study is to assess whether Multiple Sclerosis patients treated with Gilenya show a beneficial change over time in bone mass density and bone turnover markers as compared to matched controls treated with alternative FDA approved therapy or no therapy.

Clinical Trial Description

To assess the effect of Gilenya on the rate of decline in bone mass density and expression of selected bone turnover biomarkers in ambulatory subject with a relapsing form of Multiple Sclerosis compared to control subjects matched for age, race, gender, duration of disease, and disability on an alternative FDA approved disease modifying therapy or no therapy at 24 months compared to baseline. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01811290
Study type Observational
Source Simnad, Virginia, M.D.
Contact
Status Active, not recruiting
Phase N/A
Start date January 2013
Completion date December 2018
View Details
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