Multiple Sclerosis Clinical Trial
Official title:
Assessment of Subject Use of the Rebiject II Injection Device According to Nurse Examination of Subject Accuracy in 10 Steps as a Dummy Demonstration
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central
nervous system (CNS) and is one of the most common causes of neurological disability in
young adults. Rebif is licensed in the United Kingdom for the treatment of relapsing MS and
is given 3 times per week by subcutaneous injection. The Rebiject II device is an
autoinjector which allows patients easier administration of their Rebif injections.
Prior to treatment, patients receive training on the use of the device and its maintenance.
Currently, all treatments for MS are injectable and require long term patient commitment.
Rebiject has been developed to improve patient convenience and comfort but does require
multiple steps to be carried out in order for the injection to be delivered correctly.
Reports from our local call centre and nurse advisors suggest that inaccuracies of use with
the Rebiject device are common. By raising awareness of the level of inaccuracy and
determining which steps patients are most likely not to complete correctly, modified
training programs or modifications to current subject training may be put into place to
address these issues. It is also important to demonstrate the link between poor use of the
medication device and increased relapse rates or increased injection site reactions.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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