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Tysabri Effects on Cognition and Neurodegeneration in Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:
Tysabri Effects on Cognition and Neurodegeneration in Multiple Sclerosis

Clinical Trial Summary

The long-term objective is to further establish the role of Tysabri in preventing neurological degeneration in multiple sclerosis (MS) and to establish powerful and efficient new markers for neurological degeneration in MS. The study intends to correlate cognition with two instruments and their measurements-MRI and OCT (optical coherence tomography).

Clinical Trial Description

The specific aims are:

1. To determine the effects of Tysabri on cognition (memory, thought processes, etc.)

2. To determine the effects of Tysabri on specific MRI markers for cognitive dysfunction

3. To determine the effects of Tysabri on retinal nerve fiber layer thickness (RNFL) using optical coherence tomography (OCT), a special instrument used in ophthalmology ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01071512
Study type Interventional
Source University of Chicago
Contact
Status Completed
Phase N/A
Start date April 2010
Completion date January 2016
View Details
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