Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Oct

Multiple Sclerosis Clinical Trial

Official title:

Evaluation of Macular and Retinal Nerve Fiber Layer Thickness Measurements for Detection of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution Optical Coherence Tomography.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01024985
• Other study ID #: 0190/09
• Status: Recruiting
• Phase: N/A
• First received: December 2, 2009
• Last updated: June 24, 2010
• Start date: September 2009
• Est. completion date: December 2011

Study information

• Verified date: June 2010
• Source: University of Sao Paulo
• Contact: mario luiz r monteiro, phd
• Phone: 55 11 30697871
• Email: mlrmonteiro[@]terra.com.br
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to determine the ability of STRATUS OCT and high resolution OCT to detect and to quantify the neural loss in multiple sclerosis and neuromyelitis optica and its subtypes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: December 2011
• Est. primary completion date: December 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 15 Years to 60 Years

Eligibility

Inclusion Criteria:

• clinical diagnosis of multiple sclerosis or neuromyelitis optica

• age between 15 and 60 years

• BCVA better than 20/400

• no optic neuritis crisis in the last 6 months

Exclusion Criteria:

• diagnosis of glaucoma, opacities or disc anomalies

• diagnosis of macular disease

• disc swelling at fundoscopy

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Multiple Sclerosis
• Neuromyelitis Optica
• Sclerosis

Locations

Country	Name	City	State
Brazil	Hospital Das Clinicas Medical School of University of Sao Paulo	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil,