Safety of Polyphenon E in Multiple Sclerosis Pilot Study

Status Completed

Clinical Trial Summary

This study is an open label 6 month study. All subjects will be treated with Polyphenon E (400 mg EGCG twice a day) for six months. The main outcome of this pilot phase will be safety. Secondary outcomes are the change in NAA levels over 6 months as measured by MR-spectroscopy. NAA levels are a marker of neuronal function. We think that Polyphenon E will protect neurons and thus increase NAA levels.

Clinical Trial Description

Additional clinical data include changes in EDSS, MS functional composite and cognitive testing. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00836719
Study type	Interventional
Source	Louisiana State University Health Sciences Center in New Orleans
Contact
Status	Completed
Phase	Phase 1
Start date	February 2009
Completion date	November 2010

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