Multiple Sclerosis Clinical Trial
Official title:
A Double Blind, Randomised, Parallel Group Study to Assess the Efficacy, Safety and Tolerability of Cannabis Based Medicine 1:1 THC:CBD Compared With Placebo for the Treatment of Spasticity in Patients With Multiple Sclerosis.
The purpose of this study is to evaluate the efficacy, safety and tolerability of Sativex® in subjects diagnosed with MS and spasticity.
This was an eight week (two weeks baseline, six weeks treatment), multicentre, double blind, randomised, placebo controlled parallel group study to evaluate the efficacy, safety and tolerability of Sativex® in subjects diagnosed with MS and spasticity. Subjects were screened to determine eligibility and completed a two week baseline period. Subjects then returned to the site for assessment, randomisation and dose introduction. Visits occurred at the end of treatment week two and at the end of the study (treatment week six) or withdrawal. ;
Status | Clinical Trial | Phase | |
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Completed |
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Risk Perception in Multiple Sclerosis
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Completed |
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Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis
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N/A | |
Recruiting |
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Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis
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Phase 1/Phase 2 | |
Completed |
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Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With Betaferon
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Completed |
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Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
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Phase 2 | |
Completed |
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5-HT7 Receptor Implication in Inflammatory Mechanisms in Multiple Sclerosis
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Active, not recruiting |
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Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
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Completed |
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Integrating Caregiver Support Into MS Care
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N/A | |
Completed |
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Feasibility and Reliability of Multimodal Evoked Potentials
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Recruiting |
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Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
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N/A | |
Withdrawn |
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Orofacial Pain in Multiple Sclerosis
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Completed |
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Cortical Lesions in Patients With Multiple Sclerosis
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Recruiting |
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Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
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N/A | |
Active, not recruiting |
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Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis
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Phase 2 | |
Completed |
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Effect of Home Exercise Program on Various Parameters in Patients With Multiple Sclerosis
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N/A | |
Recruiting |
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Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients
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Phase 1 | |
Completed |
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iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple Sclerosis
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N/A | |
Completed |
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Cognitive Functions in Patients With Multiple Sclerosis
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Completed |
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Combined Exercise Training in Patients With Multiple Sclerosis
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N/A | |
Completed |
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BENEFIT 15 Long-term Follow-up Study of the BENEFIT and BENEFIT Follow-up Studies
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Phase 4 |