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MRI clinical trials

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NCT ID: NCT04108754 Completed - MRI Clinical Trials

Small-vessel Disease Burden and Early Risk of Stroke After Transient Ischemic Attack

TIA
Start date: August 1, 2018
Phase:
Study type: Observational

Predicting the risk of stroke remains a challenge in the management of transient ischemic attack (TIA). In addition to clinical variables, morphological features such as the presence of a diffusion weighted sequence (DWI) lesion and carotid stenosis of at least 50% improve risk stratification and are considered in the literature. score ABCD3-I1. Several studies have shown that brain microhemorrhages are associated with the risk of early stroke in patients with TIA. Data on white matter hypersignals on the T2-weighted sequence or FLAIR (FLuid Attenuated Inversion Recovery) are more conflicting. The global microangiopathic load, including the gaps, the hypersignals of the white matter, the perivascular spaces visible on MRI in the basal ganglia, especially when they are very numerous (> 20) and the gaps, have recently been described as being associated with stroke risk within 2 to 3 years of TIA or ischemic stroke. To date, the predictive value of global microangiopathic burden on early stroke risk in the course of TIA is not known.

NCT ID: NCT03684733 Completed - MRI Clinical Trials

Magnetic Resonance Breast Tissue Characterisation to Improve Risk Stratification for Breast Cancer

MR-BTC
Start date: March 13, 2017
Phase:
Study type: Observational

This is a combination retrospective/prospective observational study with two arms:

NCT ID: NCT03660852 Completed - Stroke Clinical Trials

Impact of a Magnetic Resonance Imaging (MRI) Scanner Exclusively Dedicated to Emergency in the Clinical Management of Patients Presenting With Diplopia or Dizziness

IRM-DU
Start date: July 24, 2018
Phase:
Study type: Observational

IRM-DU is a prospective observational single center study conducted in an emergency department to evaluate the impact of a MRI scanner exclusively dedicated to emergency in the clinical management of patients presenting with dizziness or diplopia. The study will compare 2 strategies : after and before availability of a MRI scanner dedicated to emergency. The primary endpoint is the proportion of patients with a diagnosis of stroke confirmed by imaging (MRI or Computed tomography (CT)) in the group "before implementation of the emergency MRI scanner" and the group "after implementation of the emergency MRI scanner". The hypothesis is that the availability of a MRI scanner dedicated to emergency will improve the diagnosis of stroke in patients presenting with dizziness or diplopia, and will reduce Emergency Department stay, hospital stay and hospitalisation costs.

NCT ID: NCT03381885 Completed - Back Pain Clinical Trials

Natural Experiment: "Gentle Nudge" Intervention, Eliminating Phone Call Requirement

LBP-ED
Start date: February 2015
Phase: N/A
Study type: Interventional

Back pain costs the U.S. over $100 billion annually, and much of this spending is wasteful due to the overuse of advanced diagnostic imaging. Despite prominent clinical guidelines and the nationally recognized Choosing Wisely campaign discouraging use of costly and low value imaging, magnetic resonance imaging (MRI) and computed tomography (CT) studies remain frequently overused. Real-time electronic clinical decision support (CDS) at the point of care has been increasingly emphasized as an important strategy to improve the value of back pain management; however, studies suggest that CDS at best only modestly influences practice patterns. The aim is to implement a behavioral economic-based intervention in the ED to promote the use of CDS system.

NCT ID: NCT03333447 Completed - MRI Clinical Trials

Retrospective and Prospective Observational Study of MRI Changes in Bone and Visceral Lesions of Patients With Type 1 Gaucher Disease Treated With VPRIV® (Velaglucerase Alfa)

EIROS
Start date: January 17, 2017
Phase:
Study type: Observational

This study with standardized reading MRIs, will provide for the first time objective and quantified data on organomegaly (liver and spleen volumes) as well as bone alteration (Bone Marrow Burden11) of French patients treated with VPRIV®. These data will help to better assess the impact of this treatment on these parameters. The result of this study will also answer in part to the request of the French Transparency Commission (CT: Commission de Transparence) of the French National Health Authority to provide them with data of French patients treated with VPRIV®.

NCT ID: NCT02988531 Completed - Clinical trials for Coronary Artery Disease

Validation of PET-MRI for Cardiovascular Disease

Start date: February 9, 2017
Phase: N/A
Study type: Interventional

To determine whether PET-MRI can obtain comparable images to PET-CT in those with coronary artery disease.

NCT ID: NCT02868671 Completed - Clinical trials for Mild Traumatic Brain Injury

Acupuncture for Mild Traumatic Brain Injury:A Functional Magnetic Resonance Imaging Study

Start date: August 2016
Phase: N/A
Study type: Interventional

The overall goal of this study is to examine if acupuncture intervention can reduce the post-concussion symptom (PCS), and affective and cognitive complaints among mild traumatic brain injury (TBI). This study also hypothesized that compared to those in the sham acupuncture and waiting list control groups, patients in the real acupuncture group will have fewer symptoms of depression, sleep problems and post-concussion symptoms.

NCT ID: NCT02548819 Completed - MRI Clinical Trials

University Hospital Cardiac Device MR Registry: The Safety of MR Imaging in Patients With Implanted Cardiac Devices

CDMR
Start date: September 2015
Phase: N/A
Study type: Observational [Patient Registry]

A single-center registry to prospectively evaluate the safety of non-cardiac/non-thoracic magnetic resonance imaging (MRI) in patients with implanted cardiac devices (pacemakers and implantable cardioverter defibrillators).

NCT ID: NCT02200809 Completed - Prostate Cancer Clinical Trials

MR-guided Focal Laser Ablation of the Prostate

Start date: July 2014
Phase: N/A
Study type: Interventional

Purpose of the investigators study is to determine the short and medium term histological cancer control of focal therapy using MR-guided focal laser ablation therapy in the treatment of localised prostate cancer.

NCT ID: NCT01578694 Completed - MRI Clinical Trials

Characterization of Proteoglycan Depletion in Femoroacetabular Impingement With T1ρ Magnetic Resonance Imaging (MRI)

Start date: July 2007
Phase: N/A
Study type: Interventional

Magnetic resonance imaging (MRI) has proven to be one of the best ways to image articular cartilage. A tremendous amount of research has focused on cartilage imaging with an emphasis of early-osteoarthritis (OA) characterization. One of the techniques which has shown great promise is the imaging technique called T1ρ . The advantage of this pulse sequence is that it is sensitive to proteoglycans (PG), a major macromolecule degraded in OA. The study objective is to determine if T1ρ can acutely assess PG content in femoroacetabular impingement (FAI) which may allow physicians to differentiate between normal and early-OA cartilage states in FAI patients.