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Motor Activity clinical trials

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NCT ID: NCT06397170 Recruiting - Stroke Clinical Trials

Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.

NCT ID: NCT06247423 Recruiting - Nerve Block Clinical Trials

High-frequency Alternating Current Stimulation for Tremor in Parkinson's Disease.

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized, double-blind, placebo-controlled, crossover study is to test the effectiveness of 10 kilohertz (kHz) high-frequency transcutaneous stimulation for tremor in people with Parkinson's disease. The main questions it aims to answer are: - Compare the effectiveness between sham stimulation and real stimulation (10kHz) for different types of tremors [rest tremor, postural tremor, kinetic tremor], fine motor skills, and maximal isometric handgrip strength. - Register adverse events, the blinding success of participants and evaluator, and subjective perception of tremor improvement. Participants will perform the following tasks in an "off" state (without levodopa and dopamine agonists medication). All of them were performed on the upper limb with more tremor. - Rest Tremor: Forearm on the armrest, count backward from 100 to 0 as fast as possible for 1 minute and 30 seconds. - Postural Tremor: Extend the arm parallel to the floor (90º shoulder flexion with the forearm extended) for 30 seconds. - Kinetic Tremor: Hold a cup by the handle, raise it close to the mouth for 3 seconds, then return to the initial position. - Fine Motor Skills: Complete the nine-hole peg test, placing pegs into holes as quickly as possible. - Handgrip Strength: Squeeze the device as strongly as possible for 3 seconds, then rest for 15 seconds.

NCT ID: NCT06174740 Recruiting - Aging Clinical Trials

Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults

NMSOA
Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to examine changes in the brain, behavior, and personal experience when music is used to guide learning of finger movement sequences (compared to visual stimuli alone) in healthy older adults. The main research questions this study aims to answer are: 1. Is auditory-based motor training associated with increased structural integrity of brain white matter tracts (connecting auditory-motor regions) compared to motor training with visual cues only? 2. Is auditory-based motor training (as compared to visual clues only) associated with increased brain cortical thickness, and changes in brain activation while performing a task in the MRI and while at rest, in auditory and sensorimotor regions? 3. Does auditory-based motor training lead to greater motor improvement on the trained task compared to a visually cued motor training? 4. Does auditory-based motor training lead to greater improvement on thinking, movement, and self-reported wellbeing measures, compared to visual cues alone? In an 8-week home training, participants will be randomized into either the music-cued motor learning (Experimental Group) or visually cued only condition (Control Group), participants will complete the following measures before-and-after the training is administered at week 1 and in the end of the 8-week trial: - MRI scans (structural and functional) - Behavioral measures (motor, cognition) - Questionnaires administered pre-and-post training (psychosocial functioning). - Questionnaires administered once only (personality traits, musical background) - In between measures, participants will follow an online computer-based training at home of 20 minutes per session, 3 times per week for 8 weeks, for a total of 24 sessions constituting 8 hours of training.

NCT ID: NCT06066619 Recruiting - Motor Activity Clinical Trials

Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?

Start date: January 10, 2024
Phase: N/A
Study type: Interventional

This clinical trial aims to investigate the effects of a 70-day consumption of cranberry juice on cognitive and motor accuracy, mental and physiological stress, and stress response in healthy men and women between the ages of 30 and 55 who engage in multitasking. The trial will utilize a randomized, double-blinded, placebo-controlled design. It is worth noting that studies have shown that over half of middle-aged Americans experience stress, which can lead to cognitive decline and depression. Previous clinical trials have indicated that consuming polyphenol-rich foods can have positive effects on cognitive function in humans. However, no study to date has examined the long-term effects of cranberry juice consumption on cognitive performance, mental stress, and stress response specifically in individuals engaged in multitasking. Based on this gap in knowledge, the investigators hypothesize the following: (1) chronic consumption of cranberry juice will improve cognitive and motor accuracy, as well as mental and psychological stress responses in young adults subjected to intense multitasking. (2) cranberry juice consumption will alleviate the negative consequences of frequent intense multitasking, such as fatigue, mood fluctuations, cognitive impairment, and memory issues. Additionally, it is expected to have a positive impact on stress biomarkers and neurotransmitter levels. By conducting this clinical trial, the investigators aim to shed light on the potential benefits of cranberry juice consumption in improving cognitive performance, mitigating mental stress, and positively influencing stress responses in individuals who engage in intense multitasking.

NCT ID: NCT05925231 Recruiting - Motor Activity Clinical Trials

Variability of Healthy People and People After Stroke Results in the Box and Block Test

Start date: July 1, 2023
Phase:
Study type: Observational

Main aim of the study is to find out how many attempts of each subtest in the Box and Block Test should be done in clinical practice during testing people after stroke who are 20-64 years old.

NCT ID: NCT05912530 Recruiting - Cognitive Change Clinical Trials

The Influence of Gender on Dual Task Performance in Young Healthy Adults

Start date: June 30, 2023
Phase:
Study type: Observational [Patient Registry]

Dual tasking (DT), or the act of conducting multiple, simultaneous tasks, is wide spread in daily life .In particular, the vast majority of mobility tasks we complete (e.g., standing, walking, stepping, etc.) occur while distracted by another motor and/or cognitive task. A common feature of DT is that performance on one or both tasks is diminished when completed together .Understanding the relationship between gender and dual task performance is important because this knowledge could help inform us the development of interventions or training programs that target these differences and improve overall performance. Aims: To investigate the gender-related differences in single task performance through motor torque, cognitive tasks and walking speed, and the combined dual-task costs considering both motor and cognitive performance in a sample of young adults

NCT ID: NCT05870072 Recruiting - Exercise Clinical Trials

The Effect of Kinesthetic Motor Imagery Training and Dual Task Training on Cognitive and Motor Functions in Healthy Youth

Start date: April 5, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the effects of kinesthetic motor imagery training and dual-task training on cognitive and motor functions in healthy young people. The main question[s] it aims to answer are: - Kinesthetic motor imagery training and dual-task training do not affect cognitive and motor functions in healthy young people. - Kinesthetic motor imagery training and dual-task training affect cognitive and motor functions in healthy youth. - In healthy young people, kinesthetic motor imagery training is more effective on cognitive functions than dual-task training. - In healthy young people, dual task training is more effective on motor functions than kinesthetic motor imagery training. Participants will be divided into 3 groups, taking into account the inclusion and exclusion criteria. Participants in each group will be asked to fill out the sociodemographic form before starting the training. Then, initial assessments were the Motion Image Questionnaire-3 to measure motor imagery ability, and the Box and Block Test for mental stopwatch; Stroop Test to measure cognitive functions; In order to evaluate the dual-task performance, the measurement of the dual-task effect and the Berg Balance scale, which evaluates balance as a motor function, and the Y test, which is frequently used in healthy individuals, will be applied. In the balance exercises group, the participants will do the determined balance exercises 3 days a week for 6 weeks, accompanied by a physiotherapist. In the double-task training group, the participants will perform the cognitive tasks in addition to the determined balance exercises, 3 days a week for 6 weeks, accompanied by a physiotherapist. In kinesthetic motor imagery group, the participants will do the physically determined balance exercises in the first session. Participants will participate in imagery exercises, 3 sessions a week for 6 weeks. Visualization studies will be performed in a quiet environment with the eyes closed, accompanied by a physiotherapist, and whether the participants perform a real motor imagery will be examined by evaluating their autonomic functions. At the end of 6 weeks, initial evaluations will be repeated in all groups. The investigators will compare dual-task training group, kinesthetic motor imagery training group and balance exercises group to see if changes in cognitive and motor function.

NCT ID: NCT05820321 Recruiting - Physical Inactivity Clinical Trials

Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in which will ingest beet juice with or without NO3 in its composition with a 8-day washout interval.

NCT ID: NCT05718427 Recruiting - Clinical trials for Attention Deficit Disorder With Hyperactivity

Effect of ASI on Sensory, Motor, Cognitive, Behavioral Skills and Social Participation in Children With ADHD

ASI-ADHD
Start date: March 29, 2023
Phase: N/A
Study type: Interventional

Attention Deficit Hyperactivity Disorder (ADHD) is a very common neurodevelopmental disorder in childhood characterized by short attention span, impulsivity and hyperactivity. It is also known that sensory integration problems are seen together with the basic symptoms of ADHD. Studies indicate that children with ADHD have difficulties in perceiving and processing sensory stimuli, and in relation to this, they have difficulty in producing appropriate sensory responses at school, at home and in social environments. However, it was observed that the interventions related to ADHD did not focus on the sensory-motor dimension enough, and focused more on cognitive or social skills. Although current research indicates the presence of sensory integration disorder in children with ADHD, there are no studies showing the effectiveness of sensory integration intervention. Our study was planned to examine the effect of Ayres Sensory Integration intervention on sensory-motor, cognitive, behavioral skills and social participation in children with ADHD. Materials and Methods: After the evaluation, 90 children with ADHD will be included in the study by dividing them into intervention (n=45) and control (n=45) groups by simple randomization method. Ayres Sensory Integration Therapy intervention will be applied to the intervention group for 10 weeks, 3 times a week, with a session duration of 1 hour, while the control group will continue the drug treatment and after a waiting period of 10 weeks, Ayres Sensory Integration Therapy will be applied after the second evaluation. Participants, Sensory Profile (SP), Sensory Integration and Praxis Test (SIPT), Emotion Regulation Checklist (ERC), Stroop Test TBAG Form (Stroop TBAG), Childhood Executive Functions Inventory (CHEXI), Participation and Environment Scale for Children and Adolescents (PEM-CY), Conners Teacher Rating Scale (CTRS), Conners Parent Rating Scale (CPRS), Bruininks-Oseretsky Motor Proficiency Test-2 (BOT-2) and Goal Achievement Scale (GAS) both before and before intervention. and post-group change as well as between-group differences will be evaluated.

NCT ID: NCT05661617 Recruiting - Motor Activity Clinical Trials

The Influence of Laterality on the Performance of Healthy Women in Selected Standardized Tests

Start date: January 19, 2023
Phase:
Study type: Observational

The aim of the research study is to find out how the results of healthy women aged 20-24 years (inclusive) differ in the Nine Peg Test, the Purdue Pegboard Test and the Box and Block Test, depending on the laterality of the research participants and the order of the performed subtests of the investigated tests. In this way, it will be preliminarily determined whether it is necessary to create normative data separately for right-handed and left-handed people for the tests.