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Mood Disorders clinical trials

View clinical trials related to Mood Disorders.

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NCT ID: NCT01149135 Completed - Clinical trials for Seasonal Affective Disorder

Low Intensity 'Blue Light' Treatment of Seasonal Affective Disorder

Start date: October 2008
Phase: N/A
Study type: Interventional

One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winter depression is a disturbance of circadian rhythms. Since the circadian system is especially sensitive for the blue portion of the light spectrum, a new light therapy device with more blue light (blue enriched polychromatic light) was tested for its efficacy to treat SAD. In chronobiological terms this light is hypothesized to be more potent in inducing non-visual effects. In the present study fluorescent tubes that emit a high portion of short wavelength light on top of the normal wavelengths are tested for its superiority in treating SAD. This blue-enriched light (colour temperature 17000 ºK) is compared to standard light treatment (5000 º K) in SAD patients.,In a earlier study it was shown that the therapeutic effect of blue enriched light were equal to standard light treatment using light in both conditions with an intensity of 10 000 lux. In the present study, blue enriched light with an intensity of 750 lux was used, because of the possible saturation effect in the former study. The investigators hypothesise that blue- enriched light with a low intensity improve the therapeutic effects of light treatment leading to a higher response or the same response in a shorter time schedule compared to standard light treatment.

NCT ID: NCT01136278 Completed - Clinical trials for Substance-Related Disorders

Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)

Start date: July 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determinate the effect of a pre-treatment with centrally acting alpha2-receptor agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that clonidine will attenuate the subjective and cardiovascular response to MDMA.

NCT ID: NCT01125579 Completed - Affective Disorders Clinical Trials

Effectiveness of NEURAPAS Balance in Children With Nervous Restlessness

Start date: March 2008
Phase:
Study type: Observational

Purpose: To document data on effectiveness of NEURAPAS® balance (NPB) in the treatment of nervous restlessness in children aged 6 to 12. Each patient is treated with NPB. No placebo group is established. Course and severity of symptoms is documented by a questionnaire on 13 common symptoms of nervous restlessness and a Visual Analogue Scale (VAS). A standardized questionnaire (Parent Child Behaviour Checklist (CBCL/4-18)) is completed. Choice and doses of therapy are at the respective physician's discretion. The planned treatment and observation period is 2 - 4 weeks.

NCT ID: NCT01106313 Completed - Depression Clinical Trials

Insulin Resistance in Patients With Major Depression

Start date: July 2009
Phase: N/A
Study type: Observational

The purpose of this study is to study the relationship between insulin and glucose action and neuropsychological functioning (memory, attention, general thinking abilities) in persons with depression.

NCT ID: NCT01048294 Completed - Clinical trials for Seasonal Affective Disorder

Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)

Start date: October 2005
Phase: N/A
Study type: Interventional

One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winterdepression is a disturbance of circadian rhythms. Since the circadian system is especially sensitive for the blue portion of the light spectrum, a new light therapy device with more blue light (blue enriched polychromatic light) was tested for its efficacy to treat SAD. In chronobiological terms this light is hypothesized to be more potent in inducing non-visual effects. In the present study fluorescent tubes that emit a high portion of short wavelength light on top of the normal wavelengths are tested for its superiority in treating SAD. This blue-enriched light (colour temperature 17000 ºK) is compared to standard light treatment (5000 º K) in SAD patients., The investigators hypothesise that blue- enriched light improve the therapeutic effects of light treatment leading to a higher response or the same response in a shorter time schedule compared to standard light treatment.

NCT ID: NCT01047124 Recruiting - Clinical trials for Chronic Unipolar Depressive Disorder

Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is determine whether a specialised mood disorder service, which offers tailored psychological and pharmacological treatment, is more effective in the treatment of chronic unipolar depressive disorder then treatment as usual.

NCT ID: NCT01032421 Completed - Mood Disorders Clinical Trials

Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes

IVF
Start date: January 2006
Phase: Phase 2
Study type: Observational

The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment. The secondary goal of this study is to explore psychological profiles and coping mechanisms of women undergoing IVF, and to identify the ones that are associated with successful psychological adaptation to the process and a successful biological outcome.

NCT ID: NCT01030276 Recruiting - Clinical trials for Seasonal Affective Disorder

Bright Light Therapy in Seasonal Affective Disorder (SAD)

VAHAVA
Start date: October 2009
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the efficacy of bright light therapy in SAD. This is a placebo-controlled, double-blind randomized controlled trial (RCT).

NCT ID: NCT01003132 Completed - Schizophrenia Clinical Trials

Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis

PACT
Start date: October 2009
Phase: N/A
Study type: Interventional

This research investigates a new talking therapy aimed at helping people to come to terms with the experience of psychosis. The new therapy is called Acceptance and Commitment Therapy for psychosis (PACT). PACT aims to help people: 1. Develop a sense of "mindfulness." Mindfulness allows you to be fully aware of your here-and-now experience, with an attitude of openness and curiosity. It is hoped that this will help reduce the impact of painful thoughts and feelings. 2. Take effective action that is conscious and deliberate, rather than impulsive. It is hoped that this will allow people to be motivated, guided, and inspired by the things that they value in life. It is hoped that PACT will help to reduce the level of distress that individuals diagnosed with psychosis have been experiencing and help them to stay well in the future.

NCT ID: NCT00990067 Completed - Clinical trials for Substance-Related Disorders

Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)

Start date: November 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determinate the effect of a pre-treatment with the combined serotonin (5-HT) and norepinephrine (NE) transport blocker duloxetine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that duloxetine will attenuate the subjective and cardiovascular response to MDMA.