Clinical Trials Logo
  1. Home
  2. Moderate Traumatic Brain Injury
  3. NCT05108909

Rapid Diagnosis and Prognosis Recognition of Imaging and Biomarkers in Mild to Moderate Traumatic Brain Injury

MTBI - Mild Traumatic Brain Injury Clinical Trial

Official title:
Rapid Diagnosis and Prognosis Recognition of Imaging and Biomarkers in Mild to Moderate Traumatic Brain Injury

Clinical Trial Summary

The investigators will carry out multi-center and large sample research based on the Chinese population, screen the optimal diagnostic and prognosis recognition biomarkers and analyze the diagnostic critical cutoff values in patients with mild to moderate traumatic brain injury, so as to provide a substantial basis for clinical diagnosis and prognosis recognition.

Clinical Trial Description

Traumatic brain injury (TBI) is a complex disorder that comprises a spectrum of intracranial pathologies, many of which present diagnostic challenges. Detection of intracranial injuries after TBI relies on head CT, which is overused and resource intensive. Prior studies have shown the potential for blood-based brain injury biomarkers to predict the absence of intracranial injury after TBI and aid in reducing unnecessary head CT use. Furthermore, plasma biomarker concentrations in the acute phase after TBI identified patients with a suspected TBI and normal head CT who had detectable pathology on MRI. However, most of the current studies are based on the European and American population, and whether the research results are applicable to the Chinese population remains to be studied. Therefore, the investigators will carry out multi-center and large sample research based on the Chinese population, screen the optimal diagnostic and prognosis recognition biomarkers and analyze the diagnostic critical cutoff values, so as to provide a substantial basis for clinical diagnosis and prognosis recognition. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05108909
Study type Observational
Source First Affiliated Hospital Xi'an Jiaotong University
Contact Ming Zhang, phD
Phone 0086-18991232265
Email zmmri@163.com
Status Recruiting
Phase
Start date September 1, 2021
Completion date August 31, 2025
View Details
See also
  Status Clinical Trial Phase
Completed NCT04776304 - Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress Symptoms N/A
Recruiting NCT03655782 - Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury N/A
Recruiting NCT05090007 - Imaging of Injury Mechanism and Interaction of Intestinal Bacteria in Children With Mild Traumatic Brain Injury
Active, not recruiting NCT05524402 - Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI N/A
Recruiting NCT04982731 - Positive Assurance and mTBI N/A
Recruiting NCT05326100 - Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI N/A
Completed NCT03674398 - Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology N/A
Recruiting NCT04279431 - Follow-up of mTBI Patients Discharged From the ED Using Standard Clinical Triage Including BrainScope One
Completed NCT04068883 - Controlled DTI Evaluations in High School Football and Female Soccer to Evaluate Efficacy of Jugular Compression Collar N/A
Completed NCT03883451 - Evaluation of Helmet Technology and Head Impact Exposure N/A
Recruiting NCT05065099 - Online Treatment Recovery Assistance for Concussion in Kids N/A
Recruiting NCT05862571 - Screening Instruments for Measuring Visual Symptoms in Victims of Concussion
Recruiting NCT05857761 - GAIN Symptoms: Post-traumatic Headache N/A