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Doravirine and Weight Gain in Antiretroviral Naive — DAWN  

Obesity Clinical Trial

Official title:
Effect of Modified, Rapid-start, DOR/3TC/TDF or DOR + FTC/TAF or BIC/FTC/TAF on Body Weight and Composition, Metabolic Risk Parameters, and Measures of Bone Strength in Treatment-Naïve Black and Hispanic Women With HIV-1 Infection

Clinical Trial Summary

The purpose of this study is determine whether different antiretroviral therapy (ART) changes the effects on body fat and predict the weight change in Black and Hispanic females.

Clinical Trial Description

Study is three-arm, open-label, randomized, interventional trial, in which all patients who are successfully enrolled will be randomized 1:1:1 to initiate ART therapy with Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate vs. Doravirine + Emtricitabine/Tenofovir Alefenamide, Bictegravir/Emtricitabine/Tenofovir Alafenamide. All patients will be followed or a total o 48 weeks. . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05457530
Study type Interventional
Source Prism Health North Texas
Contact
Status Withdrawn
Phase Phase 3
Start date August 1, 2022
Completion date May 3, 2023
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