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Minor Stroke clinical trials

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NCT ID: NCT06306144 Not yet recruiting - Minor Stroke Clinical Trials

Early-phase Telecare Programs for Minor Stroke

COGaDOM
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Minor strokes (few acute neurological symptoms ; NIHSS score <5), represent almost 65% of cerebrovascular ischemic events. The increasing incidence of stroke in people under 65, together with advances in diagnostic and revascularization techniques, mean that post-stroke life expectancy is now in the order of decades. Most patients with minor stroke are rapidly discharged from hospital, with follow-up focused on secondary prevention and they are offered little or no rehabilitation. However, up to 70% of patients with minor stroke experience difficulties resuming their social or professional activities, which can lead to social and economic disruption (delayed/compromised return to work) and an increased risk of depression. While some care recommendations exist for this population, in France there is no consensus nor identified care pathway for follow-up assessment or management of these patients. Furthermore, existing services are unevenly distributed across the country, and research into the effectiveness of rehabilitation is still scarce, leading to uncertainty as to which interventions should be prioritized to decrease difficulties related to cognitive impairment. Since there are currently no rehabilitation proposals in France for patients with mild cognitive impairment after mild stroke, in this trial the investigaror will investigate the effectiveness of two six-week telerehabilitation programs each consisting of a weekly session supervised by a therapist and a self-rehabilitation session. The aim of this multicenter randomized controlled trial is the evaluate the relevance and feasibility of early identification of patients eligible for a cognition-focused management proposal and the efficacy of two telecare programs, (a) psychoeducation and (b) computerized cognitive rehabilitation.

NCT ID: NCT05369637 Recruiting - Clinical trials for Transient Ischemic Attack

Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke

Start date: May 11, 2022
Phase: N/A
Study type: Interventional

The occurrence of a transient ischemic attack (TIA) or a minor stroke is frequently assumed as a temporary and non-disabling event. Nevertheless, patients can experience subtle but meaningful impairments, including a decreased performance in activities of daily living (ADLs), a high prevalence of depression, cognitive decline, physical deficits, hearing degeneration, with implications in returning to work, social relations and activities. Additionally, it has been described a higher risk of stroke among these patients, which highlights the importance of promoting secondary prevention, soon after these acute episodes. Therefore, this pilot randomized controlled trial (RCT) aims to evaluate the feasibility and the effectiveness of a three-month multidomain intervention program, composed of five non-pharmacological components which may contribute to accelerate the return to the pre-event level of functioning in patients with TIA and minor stroke. The results may guide future clinical practices and health policies aiming to reduce the overall burden of stroke.

NCT ID: NCT04945174 Recruiting - Clinical trials for Transient Ischemic Attack

Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.

NCT ID: NCT04917237 Recruiting - Stroke Clinical Trials

Non-disabling Ischemic Cerebrovascular Event With Apathy

Start date: July 10, 2021
Phase:
Study type: Observational

The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. However, few previous studies have focused on affective impairment after transient ischemic attack (TIA) and minor stroke. Stroke survivors are often described as apathetic. Even though post-stroke apathy (PSA) affects one in three stroke patients,it has not hitherto received much attention. NICE-A is a prospective study aimed to explore the association between baseline apathy and probable incident stroke in a population-based sample of TIA and minor stroke adults.

NCT ID: NCT04420351 Completed - Minor Stroke Clinical Trials

Thrombolysis of Urokinase for Minor Stroke

TRUST
Start date: October 4, 2020
Phase: Phase 3
Study type: Interventional

This trial will enroll patients that have been diagnosed with minor stroke, which has occurred within the past 6 hours. TRUST is a prospective multicenter, randomized, blinded-endpoint study to evaluate the efficacy and safety of Urokinase Thrombolysis for patients with minor stroke.

NCT ID: NCT03079674 Not yet recruiting - Clinical trials for Transient Ischemic Attack

China Registry of Non-disabling Ischemic Cerebrovascular Events

CR-NICE
Start date: June 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. In order to achieve accurate risk stratification and effective treatments, developing new diagnostic, therapeutic, and prognostic strategies is indispensable. Chinese registry of NICE is a national multi-center prospective study aimed to explore the epidemiology, new biomarkers, risk factors and prognostic models.

NCT ID: NCT02144831 Withdrawn - Clinical trials for Transient Ischemic Attacks

The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack

MENA-TIA
Start date: July 2014
Phase: Phase 4
Study type: Interventional

The primary goal of the research is to determine if 10 days of dual anti-platelet treatment is as effective as 30 days of similar treatment in the prevention of stroke, myocardial ischemia (MI) and death in patients with TIAs and minor stroke.