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A Study of Biomarkers of Mild Traumatic BRAIN Injury — BRAINI  

Mild Traumatic Brain Injury Clinical Trial

Official title:
A Prospective Clinical Study of Biomarkers of Mild Traumatic BRAIN Injury

Clinical Trial Summary

Patients with mild traumatic brain injury (mTBI) represent a burden of patients admitted to the emergency department. According to the guidelines, a cerebral CT scan is indicated after mTBI according to the specific conditions. However, variability exists regarding the respect of these CT scan indications, and less than 10% of patients will have visible brain lesions on CT scan. Recently, serum Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) biomarkers have shown ability to differentiate normal and abnormal CT scan findings after mTBI. These encouraging results prompted us to launch a prospective study using automated and quick measurements of GFAP and UCH-L1 biomarkers to validate these findings.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04032509
Study type Observational
Source University Hospital, Grenoble
Contact
Status Completed
Phase
Start date August 10, 2019
Completion date September 28, 2021
View Details
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