Traumatic Brain Injury Clinical Trial
Official title:
Intracranial Pressure After Decompressive Craniectomy
Observational study to investigate the natural course of intracranial pressure (ICP) after decompressive craniectomy (DC) using long-term telemetric ICP monitoring. Patients will have continuous ICP measurement performed during the admission to the neuro-intensive care unit (NICU) and after discharge weekly measurements sessions will be performed before and after cranioplasty.
Several studies have investigated and documented the effect of DC in lowering ICP in
intracranial hypertension following acute brain injuries, e.g. severe traumatic brain injury.
But the natural course of ICP in these patients after the acute phase in the NICU has never
been investigated. Clinical experience suggests that a DC affects cerebrospinal fluid
circulation and ICP, e.g. causing hydrocephalus or subdural hygromas.
The aim of this observational study is to document the natural course of ICP following DC and
to investigate the effect of cranioplasty on ICP. This is done by implantation of a
telemetric ICP sensor and weekly follow-up monitoring sessions after discharge from the NICU
until 1 month after cranioplasty. The monitoring sessions will include standardized body
positions to investigate postural ICP changes before and after cranioplasty. The project will
also provide experience with telemetric ICP monitoring during the acute phase in a NICU
setting.
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