Effects of Fluid Therapy on Microcirculatory Reactivity

Status Not yet recruiting

Clinical Trial Summary

Through preoperative fluid therapy, to investigate whether it can alleviate the microcirculation dysfunction after induction of anesthesia, and reduce the incidence of perioperative fluid therapy-related complications, thereby accelerating rehabilitation.

Clinical Trial Description

Patients undergoing minimally invasive coronary artery bypass graft surgery were randomly divided into crystal group, colloid group and control group. The preoperative fluid reactivity was evaluated according to the passive leg lifting test (PLR). When stroke volume increased (△SV)>16%, the patients in the crystal (carbonate Ringer solution) and the colloid group (hydroxyethyl starch solution) were treated with volume therapy, while the control group was not treated with PLR test and volume therapy. Vascular occlusion test was used to observe the effect of anesthesia induction on tissue oxygen saturation recovery slope (RecStO2) after volume therapy, Goal-directed fluid therapy was used during operation, and the postoperative microcirculation function and the incidence of related complications were observed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04982016
Study type	Interventional
Source	Beijing Anzhen Hospital
Contact	Boqun Cui, Doctor
Phone	13811868848
Email	120053376@qq.com
Status	Not yet recruiting
Phase	N/A
Start date	September 2021
Completion date	April 2022

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