Microbial Colonization Clinical Trial
Official title:
Evaluation of Patient Satisfaction and Microbiological Changes in Injectable Thermoplastic Resin and Conventional Acrylic Resin Complete Dentures
In this research, the investigators are comparing the new thermoplastic material side by side with the conventional poly methyl methacrylate for fully edentulous patients measuring their satisfaction and microbiological count.
The restoration of masticatory function and aesthetics is an important aim in dentistry
mainly when patients present with extensive tooth loss. The loss of tooth in elderly
patients not only impairs the stomatognathic system but also their psychological status and
quality of life.so an important criteria's for the success of dentures are patient's
expectations and the ability of the denture to replace the lost masticatory efficiency.
The acrylic resin was first used in 1936; it was in that time the best alternative for
vulcanized rubber. Where it is characterized by superior characteristics and became the most
popular material used since then. Nonetheless, it has some problems such as polymerization
shrinkage, weak flexural, lower impact strength, and low fatigue resistance. These often
lead to denture failure during chewing or when fall out of the patient's hand. In order to
enhance some properties of PMMA, various efforts have been taken including addition of metal
wires or plates, fibers, metal inserts, and modification of chemical structure. In recent
years, nylon polymer has attracted attention as a denture base material.
Thermoplastic nylon like materials or polyamides were introduced and first used in dentistry
in 1950. The polyamide are uniquely characterized by high esthetics especially in removable
partial dentures, where retentive components are recommended anteriorly by this material
which provide high elasticity we can make the retentive components using the same material
and eliminate the metallic clasps.
Polyamides are characterized by low weight and flexibility make it more patient satisfactory
and fortunately it has no monomer remnants that may affect patient health and causes
allergy. Thermoplastic polyamides have almost no porosity which eliminates water sorption.
The technique used for its fabrication is injection molding technique which is more
dimension accurate than packing mold technique.
Valplast was initially used just over 50 years ago and has been used in modern dentistry
since the mid-fifties. A variation of nylon, which is far more flexible and stronger than
poly methyl methacrylate resin, is used in many alternative partial dentures. Valplast
flexible dentures are used for full sets of dentures especially in cases of acrylic allergy
which represent 20% of the population.
Comparative Evaluation of Impact and Flexural Strength is done to four types of Four
Commercially Available Flexible Denture Base Materials. Valplast had the maximum impact
strength, so these materials should be used in less undercut areas for long-term interim
removable partial dentures.
A study done by investigators who evaluated the surface roughness of four thermoplastic
(polyamide: Valplast, Lucitone FRS, polyethylene terephthalate: EstheShot, and polyester:
EstheShot Bright) and two conventional acrylic (Heat-polymerizing: Urban, and Pour type
auto-polymerizing: Pro-Cast DSP) denture bases by using scratch test. The results showed
that the surface of thermoplastic denture base resins was easily damaged compared with
polymethyl methacrylate which can cause discomfort to patients and also discoloration.
Complete Dentures Made with High Impact and Flexible Resins were evaluated. There was
statistically significant difference for masticatory performance in wet and dry weight
values of hard food, but there was no statistically significant difference for masticatory
performance in wet and dry weight values of soft food between the conventional and flexible
dentures. Though masticatory efficiency and performance were found to be better for
patient's dentures made with Polymethyl methacrylate (PMMA), a statistically significant
number of patients reported that the flexible dentures were more satisfying than the
conventional dentures.
Another study was done to evaluate the patients inflamatory response. patients received
acrylic complete denture were associated with significant high levels of proinflammatory
salivary cytokines (TNF-α and IL-6) in comparison to their corresponding levels in the
thermoplastic polyamide complete denture patients. The high levels of pro-inflammatory
salivary cytokines (TNF-α and IL-6) that were found in saliva of control group patients may
be linked to their protective effect against tissue inflammation caused by release of
residual monomer.
Adherence of Candida albicans to Flexible Denture Base Material was studied and concluded C.
albicans has lesser opportunities to adhere on flexible denture than on acrylic resin
denture base materials.
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