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Clinical Trial Summary

This is a phase I clinical study to evaluate the safety and tolerability of CAR-T in patients with CD70-positive advanced/metastatic solid tumors, and to obtain the maximum tolerated dose of CAR-T and phase II Recommended dose.


Clinical Trial Description

This is a single-center, double-arm, open-label study. The study plans to set up 2 groups,Intravenous infusion group have 4 dose groups, adopting a dose-escalating 3+3 design, and plan to recruit about 12 subjects with CD70-positive advanced/metastatic solid tumors.Intraperitoneal injection group have 4 dose groups, adopting a dose-escalating 3+3 design, and plan to recruit about 12 subjects with CD70-positive advanced/metastatic solid tumors. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05420545
Study type Interventional
Source Chongqing Precision Biotech Co., Ltd
Contact Jingwang Bi, M.D
Phone 13066029387
Email jingwangbi@live.cn
Status Recruiting
Phase Phase 1
Start date December 31, 2021
Completion date December 31, 2024

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