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Clinical Trial Summary

Vulvar cancer is a rare malignancy. Surgery is the treatment of choice, but frequently causes invalidating and chronic postoperative morbidity, especially in patients with high stage disease. Theoretically, downstaging with neo adjuvant chemotherapy could shrink the tumour, making surgical treatment less extensive thereby diminishing the chance for morbidity.


Clinical Trial Description

Vulvar cancer is a rare malignancy. Surgery is the treatment of choice, but frequently causes invalidating and chronic postoperative morbidity, especially in patients with high stage disease. Theoretically, downstaging with neo adjuvant chemotherapy could shrink the tumour, making surgical treatment less extensive thereby diminishing the chance for morbidity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04161664
Study type Interventional
Source The Netherlands Cancer Institute
Contact Frederic Amant, MD, PhD
Phone 0031205129111
Email f.amant@nki.nl
Status Recruiting
Phase Phase 2
Start date January 16, 2020
Completion date January 1, 2029