Metastatic Solid Tumors Clinical Trial
Official title:
A Phase I/Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Avelumab in Chinese Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors With Expansion to Selected Indication(s)
The purpose of this study was to evaluate the maximum tolerated dose (MTD) and pharmacokinetics (PK) of Avelumab monotherapy in Chinese subjects.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
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Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET
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Phase 1/Phase 2 | |
| Recruiting |
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First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors
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Phase 1 | |
| Completed |
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Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors
|
Phase 1/Phase 2 | |
| Completed |
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Phase 1b Trial of BGJ398/BYL719 in Solid Tumors
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Phase 1 | |
| Completed |
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Phase 1 | |
| Recruiting |
NCT06031441 -
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
|
Phase 1 | |
| Completed |
NCT03059823 -
A Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors
|
Phase 1 | |
| Terminated |
NCT03573544 -
This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT03893955 -
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
|
Phase 1 | |
| Completed |
NCT00878423 -
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|
Phase 1 | |
| Withdrawn |
NCT00149019 -
Immunotherapy of Cancer Using Donor Lymphocytes Labelled With In-vitro Bispecific Antibodies.
|
Phase 2 | |
| Recruiting |
NCT03093116 -
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
|
Phase 1/Phase 2 | |
| Terminated |
NCT03854227 -
A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors
|
Phase 1 | |
| Recruiting |
NCT04094610 -
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT01543763 -
Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors
|
Phase 1 | |
| Terminated |
NCT02228811 -
A Study of DCC-2701 in Participants With Advanced Solid Tumors
|
Phase 1 | |
| Recruiting |
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Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)
|
Phase 1 | |
| Completed |
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Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.
|
Phase 1 | |
| Recruiting |
NCT05836324 -
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
|
Phase 1 | |
| Completed |
NCT03910530 -
A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors
|
Phase 1 |