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Safety and Tolerability of MSI-1436C in Metastatic Breast Cancer

Metastatic Breast Cancer Clinical Trial

Official title:
A Phase I Study of the Safety and Tolerability of Single Agent MSI-1436C in Metastatic Breast Cancer Patients

Clinical Trial Summary

This is a Phase I, open-label, dose escalation study. MSI-1436 will be administered as a single intravenous infusion twice a week for 3 weeks on a 4-week cycle.

Clinical Trial Description

This is a Phase I, open-label, dose escalation study. MSI-1436 will be administered as a single intravenous infusion twice a week for 3 weeks on a 4-week cycle. Subjects will be enrolled according to a standard Phase I Fibonacci design to receive MSI-1436. Drug infusions will last approximately 2 hours. If a subject has a dose-limiting toxicity (DLT) at any time during the study, MSI-1436 will be held and either re-started or discontinued in that subject as per the Dose Adjustments and Toxicities Guidelines. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02524951
Study type Interventional
Source Northwell Health
Contact
Status Terminated
Phase Phase 1
Start date April 2016
Completion date May 14, 2018
View Details
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