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Metabolism Disorder clinical trials

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NCT ID: NCT03386461 Completed - Clinical trials for Inflammatory Response

Effect of Exercise and Omega-3 on Metabolic Health in Elderly

EXODYA
Start date: January 5, 2017
Phase: N/A
Study type: Interventional

The aim of this project is to investigate in elderly women, the effect of combined aerobic and resistive training and concomitant supplementation with omega-3 fatty acids on adipogenesis, metabolic functions and pro-inflammatory status of adipose tissue and on systemic metabolic profile.

NCT ID: NCT03233568 Completed - Clinical trials for Overweight and Obesity

Use of Indirect Calorimetry in Obesity

Start date: April 1, 2012
Phase: N/A
Study type: Observational

The investigators will retrospectively analyze and compare data of 2 groups of overweight and obese patients: subjects who followed a diet based on Resting Energy Expenditure (REE) measured by indirect calorimetry and subjects who followed a diet based on REE estimated by the Harris-Benedict equation. Propensity score adjustment will be used to adjust for known differences between the 2 groups

NCT ID: NCT03119350 Completed - Obesity Clinical Trials

Mitochondrial Energy Metabolism in Obese Women

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

Considering that the failure of the treatment of obesity is justified by the multifactorial pathophysiology of this morbidity, the present project has the following hypotheses: 1. The occurrence of obesity is due to the derange,ent of mitochondrial energy metabolism ; 2. The unbalance is therapeutically modified through physical training ; 3. Obesity courses with the break-down in energy metabolism mitochondrial disease associated with systemic inflammatory characteristics that can be corrected through a combined long-term physical training program. This study have as objective : to analyse changes in mitochondrial function, inflammatory profile, oxidative stress and energy metabolism caused by concurrent physical training in obese women.

NCT ID: NCT03097926 Completed - Clinical trials for Bariatric Surgery Candidate

Duodenal Switch With a Standard Versus Long Alimentary Limb

Long_limb_DS
Start date: May 2013
Phase: N/A
Study type: Interventional

The aim of this study was to determine if Biliopancreatic Diversion with Duodenal Switch (BPD-DS) with a longer strict alimentary limb at the expense of a shorter biliopancreatic limb will offer significant weight lost, but with lesser gastrointestinal complaints, protein deficiency, vitamin and trace element deficit compared to standard BPD-DS.

NCT ID: NCT03035344 Recruiting - Clinical trials for Acute Lymphoblastic Leukemia, Pediatric

Study of the Intermediate Metabolism in Children With Acute Lymphoblastic Leukemia (ALL)

Start date: May 2015
Phase: N/A
Study type: Observational

Study of the intermediate metabolism in children diagnosed with ALL compared to healthy matched controls.

NCT ID: NCT03033667 Completed - Metabolism Disorder Clinical Trials

Conventional Fasting Versus Lipid/Carbohydrate Infusion for Coronary Bypass Patients

Start date: September 2014
Phase: N/A
Study type: Interventional

Comparative study between conventional fasting versus overnight infusion of lipid or carbohydrate on free fatty acids and insulin in obese patients undergoing elective first time on-pump coronary artery bypass grafting.

NCT ID: NCT03016806 Recruiting - Multiple Myeloma Clinical Trials

Umbilical Cord Blood Transplantation From Unrelated Donors

Start date: June 2015
Phase: Phase 1
Study type: Interventional

This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.

NCT ID: NCT03003754 Completed - Insulin Sensitivity Clinical Trials

Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile

Start date: June 2015
Phase: N/A
Study type: Interventional

Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children. Thus, is yet unknown what baseline health status as well as the influence of what health variable may produce more/less non-responder (NR) prevalence (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes) after exercise training in school children.

NCT ID: NCT03000140 Completed - Hypertension Clinical Trials

High-Intensity Interval Training on Pre-Hypertensive Subjects

Start date: March 2015
Phase: N/A
Study type: Interventional

Despite exercise training decrease blood pressure in 'average' terms, there is a wide interindividual variability after exercise training, being yet unknown what mode of exercise (e.g. endurance, strength, concurrent, or high intensity interval training) produce more/less non-responder (NR) prevalence (i.e., percentage of subjects who experienced a non-change/worsened response after training in some outcome).

NCT ID: NCT02978937 Completed - Metabolism Disorder Clinical Trials

Obstructive Sleep Apnea and Metabolic Health

Start date: April 2015
Phase: N/A
Study type: Observational

This is an observational study involving chart review of patients seen in the bariatric clinic since 2012 at The Ohio State University (OSU). Obese patients will be divided into two groups according to their metabolic profile (healthy vs unhealthy). The assignment to each group will be determined by the presence of diagnosis of hypertension, diabetes mellitus and/or dyslipidemia. The presence of at least 2 diagnoses will be defined as metabolically unhealthy. Then, each group will be divided based on the presence of Obstructive Sleep Apnea diagnosis. All data will be collected through a review of the patient's electronic medical record from the bariatric clinic database (the investigators will collect variables as age, gender, race, BMI, smoking status, the presence of diagnosis as Obstructive sleep apnea, hypertension, diabetes, hyperlipidemia). The investigators will analyze that data and establish if there is any correlation between sleep apnea and the subjects' metabolic profile.