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Mental Disorders clinical trials

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NCT ID: NCT04792476 Not yet recruiting - Clinical trials for First-episode Psychosis

HIIT in Patients With a First-episode Psychosis

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This study aims to estimate the effect of a 3-month High Intensity Interval Training on antipsychotic-induced weight gain in patients with a first episode of psychosis, as well as to determine whether these effects are maintained 9 months after the intervention has ended.

NCT ID: NCT04762394 Not yet recruiting - Clinical trials for Child Behavior Disorders

Epidemiology of Psychiatric Disorders in Children and Adolescent at Egypt

Start date: February 20, 2021
Phase:
Study type: Observational

Pediatric, developmental and mental health problems are more common than renal, cardiac and renal problems. Compartmental problems were often conceptualised across two broad spectrums: internalising intrapersonal problems like anxiety, depression and withdrawal and externalising problems such as Interpersonal problems such as hyperactivity and aggression. Mental disorders with long-term consequences can result in children and adolescents, undermining health compliance and reducing societies' ability to be safe and productive. As, children and adolescent have long-term deteriorating effects of mental health problems are often serious. Early detection and identification of problems are in the best interest of children, adolescents, their families, and the community as a whole. All three are important. how epidemiology can help our understanding of children and adolescent mental health: the burden of the community, measurement and tracking highly significant. This study will display the first large-scale study of psychiatric disorders in children and adolescents in the Egypt . to provide services, including prevention and intervention based on evidence of mental health, a population-representative child survey and adolescent mental estimates disorders were needed urgently

NCT ID: NCT04745819 Not yet recruiting - Clinical trials for Child Behavior Disorders

Epidemiological Screening of Psychiatric Disorders Among School Aged Children and Adolescent in Assiut Governorate

Start date: February 2021
Phase:
Study type: Observational [Patient Registry]

Paediatric behavioural, developmental, and mental health issues are more common than childhood cancers, cardiac problems, and renal problems combined. Behavioural problems have often been conceptualized along two broad spectrums: internalizing problems which are expressed in intrapersonal manifestation, such as anxiety, depression, and withdrawal; and externalizing problems which are demonstrated in interpersonal manifestation, such as hyperactivity and aggression The lack of attention to the mental health of children and adolescents may lead to mental disorders with lifelong consequences, undermines compliance with health regimens, and reduces the capacity of societies to be safe and productive. As, children and adolescent mental health problems often have serious long term debilitating effects . Early identification and treatment of these problems are in the best interest of children, adolescents, their families, and society as a whole . All three essential ways in which epidemiology can contribute to our understanding of children and adolescent mental health: community burden, measurement, and triage were of utmost importance. planning and conducting the survey. In this study the researchers will present the first large-scale survey of child and adolescent psychiatric disorders at Assiut government For adequate planning of services, including evidence-based mental health prevention and intervention, a population-representative survey of children and adolescent estimating mental disorders was urgently needed

NCT ID: NCT04674059 Not yet recruiting - Bipolar Disorder Clinical Trials

A Descriptive Study on Patients With Bipolar Disorder in Rwanda

Start date: January 1, 2021
Phase:
Study type: Observational

The aim is to provide a comprehensive assessment regarding the service provision and the accessibility to intensive mental health care in Rwanda

NCT ID: NCT04657380 Not yet recruiting - Psychosis; Episode Clinical Trials

A Mobile Application to Improve Case-management and Patient's Functioning in First Episode Psychosis

PLAN-e-PSY
Start date: December 4, 2022
Phase: N/A
Study type: Interventional

First Episode Psychosis (FEP) includes perceptual distortions, delusions and cognitive impairment with severe consequences, such as suicidal behaviour. It affects 3% of the population, mainly adolescents and young adults, the majority of with progress to a psychotic disorder. The early stages of psychotic disorders, from the first full blown symptoms to the next two to five years, represent an opportunity to targeted care and prevention. Indeed, it is a critical period with a worsened clinical prognostic when intervention is delayed, increasing the duration of untreated psychosis (DUP). Also, it is a key period to reduce mortality, as it is characterized by elevated risks of suicide and low physical health outcomes. Besides the symptomatic components, this period is also critical for self-building on educational, professional and emotional levels. Early intervention programmes involve multi-disciplinary teams, including a care coordination function, embodied by a "case manager". His missions include assessing the patient's needs, developing a care plan to meet the latter, organising access to the different components of the care plan, monitoring and evaluating care, and providing clinical follow-up. Engagement in the care process is fragile in psychotic disorders, particularly in the context of first episode psychosis with a high risk of care disengagement, often associated with a relapse. It is therefore essential that case-managers involved in FEP services have access to tools designed according to the patient needs and not solely to symptoms, in a "recovery oriented" approach, to foster the feeling of commitment of patients in their care process. The use of mobile applications for smartphones represents an interesting perspective to improve the engagement of patients with FEP in care. However, the use of an application focused on recovery is feasible and acceptable in patients with first episode psychosis enrolled in a specialised outpatient department (FEP-type service) and allows improvement on clinical criteria, such as psychotic symptoms or mood. User-centred design methods including identification of users and an inventory of their needs, prototyping with rapid iterations, is a simplification of the procedure and exploitation of existing constraints to increase the rate of use. Moreover, it has recently been shown that such a methodology is feasible in populations with a first episode of psychosis. Our hypothesis is that the use of a mobile case-management application for planning and monitoring individualised care objectives, co-designed with patients, their careers, and health professionals, improves the functioning of patients managed for a first psychotic episode, compared to usual case management practices. The originality of our project is built up on two pillars : - the use of a a mobile monitoring application, which will be used jointly by patients and case-managers, - the methodological innovation also lies in the collaborative and patient-centred design of the application The originality of our project concerns on the one hand the intervention, an application mobile follow-up, which will be used jointly by patients and case managers. The innovative character also lies at the methodological level in the collaborative and patient-centered design of the application ('user-centered design' approach).

NCT ID: NCT04631952 Not yet recruiting - Psychosis Clinical Trials

Online Exercise Intervention for Psychosis Patients Receiving Residential Care

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The main objective of this randomised controlled trial (RCT) is to investigate the immediate and long-term effectiveness of 8-week online exercise intervention for people with psychosis receiving residential care.

NCT ID: NCT04602585 Not yet recruiting - Psychosis Clinical Trials

The Effect of Psycho-education on Clinical Outcomes Among Patients With a First Episode Psychosis in Central Uganda

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Background: Psychotic disorders which the investigators have operationally defined as any of schizophrenia or schizophrenia spectrum disorder, brief psychotic episode, or bipolar affective disorders are severe forms of mental illness that contribute to significant morbidity and mortality primarily due to high rates of relapse. Delivering psycho-education messages about disease etiology, their signs and symptoms, as well as the benefits of adhering to treatment have been shown to reduce relapse among individuals with psychoses in high income countries. However, little has been done to examine the efficacy of this intervention in low resourced settings like Uganda. Objective: The study objective is to examine the efficacy of psycho-education on symptom severity, stigma and retention in care. Methods: The Investigators will recruit 80 adult patients (aged ≥18 years) who have been diagnosed with a First Episode Psychosis (FEP) and received antipsychotic medication at Butabika Hospital. Participants should be ready for discharge and reside within a 21km radius from Kampala city. The investigators will use a simple random technique to randomize the 80 participants to either receive 6 sessions of psycho-education from village health team members (VHTs) with a family member (n=40) or routine care (n=40). The investigators will collect symptom severity, stigma and retention in care data over 24 weeks. Data analysis plans: The investigators will conduct an intention to treat analysis and compare the groups at baseline, weeks 4, 12 and 24. We will assess the effects of the intervention on symptom severity. The investigators will assess for potential confounders, mediators and effect modifiers using generalized linear estimates. Between-subject analysis at week 24 will be used to assess if there is a significant difference in the mean severity scores between the 2 arms. Conclusion: Findings from this research will throw more light with regards to the preliminary efficacy of the use of psycho-education for individuals with psychosis.

NCT ID: NCT04551027 Not yet recruiting - Schizophrenia Clinical Trials

Assessing the Effect of Compensatory Cognitive Intervention Among People With Severe Mental Illness

Start date: September 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess the efficacy of a short term compensatory cognitive group intervention - the Compensatory Cognitive Training (CCT) among people with severe mental illnesses, receiving ambulatory treatment

NCT ID: NCT04517279 Not yet recruiting - Psychotic Disorders Clinical Trials

Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention

PAS-EPP
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to pilot a peer-provided, manualized intervention to increase the proportion of young people with first episode psychosis who reduce or stop substance use and improve psychiatric and functional outcomes. Coordinated specialty care teams will be randomly assigned to implement the intervention, Peer Approaches to Substances in Early Psychosis Programs (PAS-EPP), or usual care. The pilot study aims to: (a) determine if peer providers can implement PAS-EPP with adequate fidelity; (b) determine if youth and young adults engage in the intervention with peer providers and find it acceptable; (c) estimate the rates of drop-out for each of the two study arms; (d) estimate both between-participant (within-provider team) and between-team variability on key outcome measures; and (e) identify any changes needed to the intervention approach, manual, or training materials. The pilot study will set the stage for a future comparative cluster randomized trial of the intervention;

NCT ID: NCT04515173 Not yet recruiting - Clinical trials for Artificial Intelligence

Artificial Intelligence in Mental Illness Diagnosis and Treatment

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

To improve the quality of mental health services, we will develop a robot that includes disease screening, diagnosis, treatment, and follow-up. The effectiveness of robots will be verified in a prospective, randomized, multi-center clinical trial. We assume that the robot will reduce the differences in the experience of doctors of different years and will improve mental health care across the country, and improve the uneven distribution of mental health resources through remote resource sharing.