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Meniscus Tear clinical trials

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NCT ID: NCT06447142 Recruiting - Meniscus Tear Clinical Trials

The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears

Start date: June 10, 2024
Phase: N/A
Study type: Interventional

This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.

NCT ID: NCT06447129 Recruiting - Meniscus Tear Clinical Trials

Effect of NMES as an Add-On to Exercise Program in Degenerative Meniscus Tears

Start date: June 10, 2024
Phase: N/A
Study type: Interventional

This randomized-controlled trial aims to investigate the effect of NMES as an add-on to an exercise program in patients with degenerative meniscus tears.

NCT ID: NCT06041321 Recruiting - Meniscus Tear Clinical Trials

Novel Bioactive Sleeve on Pain and PROMs

Start date: December 6, 2023
Phase: N/A
Study type: Interventional

A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.

NCT ID: NCT05909865 Recruiting - Meniscus Tear Clinical Trials

PRedIcting MEniscal Tears Outcomes After Physical Therapy Treatment

PRIME
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of this multicenter non-controlled study is to develop a multivariable prediction model of pain/disability improvements in patients with meniscal tears, after a physical therapy treatment based on therapeutic exercise and education.

NCT ID: NCT05882591 Recruiting - Meniscus Tear Clinical Trials

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

Start date: October 9, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

NCT ID: NCT05799196 Recruiting - Meniscus Tear Clinical Trials

The Effectiveness of the Microfracture Technique in the Meniscal Healing

Start date: March 31, 2023
Phase:
Study type: Observational [Patient Registry]

Meniscus injuries are a very common cause of knee pain. The meniscus is a semilunar fibrocartilage structure found on the medial and lateral sides of the knee. The meniscus serves to absorb impact and protect the articular cartilage during weight-bearing activities, joint stability, proprioception, and nutrition. This has a significant effect on knee biomechanics. After the menisci are injured, the biomechanics of the knee change so that degenerative changes occur more frequently in the tibiofemoral compartment. Improvement of tibiofemoral arthrosis after meniscectomy surgery has been demonstrated in several long-term clinical studies. With increasing awareness of the importance of the meniscus in knee biomechanics, various meniscus repair techniques have been developed. In addition, several adjuvants for healing have been proposed to enhance meniscus healing. However, a study showed the meniscal repair failure rate increased from 22% to 24% at 5 years. Study found the healing rate of meniscus repair, which was accompanied by ACL repair, had a greater healing rate, 93% vs. 50%. Hemarthrosis that occurs after bony tunneling during ACL reconstruction provides a fibrin clot and an environment rich in factors that promote healing of the newly repaired meniscus. The fibrin clot provides the structural foundation for meniscus healing. Transmission factors, such as fibronectin and growth factors, are also present. Microfracture is a common procedure used for the treatment of damage to the articular cartilage in the knee. This procedure is used to stimulate the production of fibrocartilage in areas of injured cartilage. Microfractures are performed by creating 1 or more small channels (1 to 3 mm in size) that pierce the subchondral bone and release bone-forming components into the joint. Microfractures serve to promote the formation of fibrocartilage over damaged cartilage. Research in 2016 used an animal model (Capra hircus) to investigate the effectiveness of the microfracture technique on meniscus tear healing rates. They found significant healing in meniscal repair accompanied by microfracture technique (65% vs 12%). However there is still not enough research regarding the efficacy of microfracture in meniscal healing, especially among Indonesian. Therefore, the investigators aim to investigate its efficacy.

NCT ID: NCT05617807 Recruiting - Meniscus Tear Clinical Trials

Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Standard arthroscopy has been the gold standard for treatment of meniscus tears since the 1980's. The purpose of this study is to analyze the clinical outcomes of using the smaller diameter Nanoscope for partial menisectomy. The authors hypothesize that the Nanoscopic partial menisectomy patients will have less pain and return function faster than standard arthroscopy.

NCT ID: NCT05560477 Recruiting - Meniscus Tear Clinical Trials

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

Start date: April 26, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical trial is to assess the safety and efficacy of AM3101 to facilitate meniscal repair and reduce the incidence of non-healing complications and morbidities associated with a failed meniscal repair. This is a prospective, randomized, controlled, double-blinded, multi-center study.

NCT ID: NCT05335252 Recruiting - Knee Osteoarthritis Clinical Trials

Dronabinol After Arthroscopic Surgery

Start date: June 28, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pain, reduce opioid consumption and will result in few negative side effects. If this pilot study shows promising results the investigators will expand the trial to include additional arthroscopic surgeries (hip, shoulder) and other types of orthopaedic surgery.

NCT ID: NCT05322005 Recruiting - Meniscus Tear Clinical Trials

Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides

Start date: October 26, 2020
Phase: N/A
Study type: Interventional

This is a non-randomized multicentre study for the evaluation of the clinical performance and safaty of the augmentation-to-surgery and conservative treatments for the degenerative meniscopathies, with injection of polynucleotide gel.