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Meniscus Tear clinical trials

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NCT ID: NCT06041321 Recruiting - Meniscus Tear Clinical Trials

Novel Bioactive Sleeve on Pain and PROMs

Start date: December 6, 2023
Phase: N/A
Study type: Interventional

A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.

NCT ID: NCT05909865 Recruiting - Meniscus Tear Clinical Trials

PRedIcting MEniscal Tears Outcomes After Physical Therapy Treatment

PRIME
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of this multicenter non-controlled study is to develop a multivariable prediction model of pain/disability improvements in patients with meniscal tears, after a physical therapy treatment based on therapeutic exercise and education.

NCT ID: NCT05882591 Recruiting - Meniscus Tear Clinical Trials

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

Start date: October 9, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

NCT ID: NCT05875480 Completed - Rehabilitation Clinical Trials

The Effectiveness of Telerehabilitation After Arthroscopic Meniscus Repair

Start date: September 23, 2021
Phase: N/A
Study type: Interventional

This study was performed on 42 patients, who underwent arthroscopic meniscus repair surgery in the Orthopedics and Traumatology Department of Acıbadem Maslak Hospital. 42 patients randomly assigned to 14 synchronized telerehabilitation, 14 asynchronous telerehabilitation, 14 conventional physiotherapy groups and included in the study. The evaluation form created for the provision of demographic information are used. Primary outcome measures are muscle strength, range of motion (ROM) and pain intensity. Secondary outcome measures are general health profile and functional status assessment of the knee joint . Evaluation methods: All evaluations were performed in the preoperative period, 10. day, 6. week and 6. month postoperatively. ROM and pain measurements repeated every week during the 6-week rehabilitation process. Pain, general health profile and functional status assessment of the knee joint were assessed via a telerehabilitation application, Albert Health Assistant. Postoperative first day, the 14-day exercise program was taught to all patients practically and was given as a brochure. Patients in the synchronized telerehabilitation group started physiotherapy postoperative 14. day, met with the physiotherapist in real time via the Albert Health Assistant application and they were treated 2 days a week until 6. week. In the remaining days, they asked to follow the exercise videos uploaded to the Albert system, it was checked whether they are doing daily exercises, and a daily reminder message was sent via the system. The exercise program for the asynchronous telerehabilitation group was uploaded to the Albert Health Assistant as a video from the 14th day in the form of 2-week programs. It was checked over the system whether the patients apply these videos on a daily basis, and a message reminding the daily routine exercise program was sent through the system. Patients in the supervised physiotherapy group started to take supervized rehabilitation after 10-14 days postoperatively, 2 times a week until 6th week postoperatively in Maslak Acıbadem Hospital Orthopedics and Traumatology Department. ROM, Pain, functional and general health evaluations of the patients in this group were performed on the online platform. In addition, daily routine exercises will be followed over the Albert system on the days they do not come for treatment.

NCT ID: NCT05799196 Recruiting - Meniscus Tear Clinical Trials

The Effectiveness of the Microfracture Technique in the Meniscal Healing

Start date: March 31, 2023
Phase:
Study type: Observational [Patient Registry]

Meniscus injuries are a very common cause of knee pain. The meniscus is a semilunar fibrocartilage structure found on the medial and lateral sides of the knee. The meniscus serves to absorb impact and protect the articular cartilage during weight-bearing activities, joint stability, proprioception, and nutrition. This has a significant effect on knee biomechanics. After the menisci are injured, the biomechanics of the knee change so that degenerative changes occur more frequently in the tibiofemoral compartment. Improvement of tibiofemoral arthrosis after meniscectomy surgery has been demonstrated in several long-term clinical studies. With increasing awareness of the importance of the meniscus in knee biomechanics, various meniscus repair techniques have been developed. In addition, several adjuvants for healing have been proposed to enhance meniscus healing. However, a study showed the meniscal repair failure rate increased from 22% to 24% at 5 years. Study found the healing rate of meniscus repair, which was accompanied by ACL repair, had a greater healing rate, 93% vs. 50%. Hemarthrosis that occurs after bony tunneling during ACL reconstruction provides a fibrin clot and an environment rich in factors that promote healing of the newly repaired meniscus. The fibrin clot provides the structural foundation for meniscus healing. Transmission factors, such as fibronectin and growth factors, are also present. Microfracture is a common procedure used for the treatment of damage to the articular cartilage in the knee. This procedure is used to stimulate the production of fibrocartilage in areas of injured cartilage. Microfractures are performed by creating 1 or more small channels (1 to 3 mm in size) that pierce the subchondral bone and release bone-forming components into the joint. Microfractures serve to promote the formation of fibrocartilage over damaged cartilage. Research in 2016 used an animal model (Capra hircus) to investigate the effectiveness of the microfracture technique on meniscus tear healing rates. They found significant healing in meniscal repair accompanied by microfracture technique (65% vs 12%). However there is still not enough research regarding the efficacy of microfracture in meniscal healing, especially among Indonesian. Therefore, the investigators aim to investigate its efficacy.

NCT ID: NCT05715177 Completed - Meniscus Tear Clinical Trials

Influence of Kinesio Tapping on Quadriceps Muscle Peak Torque and Bioelectrical Activity After Meniscectomy

Start date: February 6, 2023
Phase: N/A
Study type: Interventional

A Pretest post-test control group design will be used to investigate the effect of kinesio taping on electrical activity and peak torque of the quadriceps femoris muscle during concentric and eccentric contraction after arthroscopic partial meniscectomy (APM) surgery.

NCT ID: NCT05617807 Recruiting - Meniscus Tear Clinical Trials

Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Standard arthroscopy has been the gold standard for treatment of meniscus tears since the 1980's. The purpose of this study is to analyze the clinical outcomes of using the smaller diameter Nanoscope for partial menisectomy. The authors hypothesize that the Nanoscopic partial menisectomy patients will have less pain and return function faster than standard arthroscopy.

NCT ID: NCT05560477 Recruiting - Meniscus Tear Clinical Trials

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

Start date: April 26, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical trial is to assess the safety and efficacy of AM3101 to facilitate meniscal repair and reduce the incidence of non-healing complications and morbidities associated with a failed meniscal repair. This is a prospective, randomized, controlled, double-blinded, multi-center study.

NCT ID: NCT05505747 Not yet recruiting - Meniscus Tear Clinical Trials

Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair

Start date: July 2025
Phase: Phase 2/Phase 3
Study type: Interventional

Arthroscopic meniscal procedures are the most commonly performed orthopaedic procedure in the U.S. affecting 15% of Americans ages 10-65 years. Meniscus injury is also known to increase the risk of posttraumatic osteoarthritis (PTOA). The current randomized clinical trial will test a novel intervention after meniscal repair that combines an oral senolytic fisetin and real-time biofeedback program to restore joint loading and subsequent return to activity.

NCT ID: NCT05491564 Not yet recruiting - Meniscus Tear Clinical Trials

SoftStitch™ for All-Inside Meniscal Repair: Comparative Analysis of Patient Reported Outcome Measures

Start date: July 1, 2023
Phase:
Study type: Observational

Acute and traumatic knee meniscus tears are a frequent occurrence. Evidence shows meniscal repair results in more favorable patient reported outcomes and articular cartilage preservation.1 This prospective, multicenter, single cohort, longitudinal study is intended to evaluate the effectiveness and safety profile of SoftStitch™ when used as standard of care for All-Inside Meniscal Repair. Electronic Patient Reported Outcome Measures (ePROM), functional assessments of the knee, Adverse Events of interest and Adverse Device Effects will be assessed.