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Meningiomas clinical trials

View clinical trials related to Meningiomas.

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NCT ID: NCT06466720 Not yet recruiting - Quality of Life Clinical Trials

Measuring and Mapping Cognitive Decline After Brain Radiosurgery

CoDeB-Rad
Start date: June 10, 2024
Phase:
Study type: Observational
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NCT ID: NCT02939833 Not yet recruiting - Meningiomas Clinical Trials

Effects of Scalp Nerve Blocks on Systemic Inflammation

Start date: January 2017
Phase: N/A
Study type: Interventional

Patients undergoing meningeoma resection surgery will be randomly assigned to two groups. One group will receive scalp nerve blocks with 0.5% ropivacaine, whereas the other group will receive scalp nerve blocks with 0.9% saline after anesthesia induction and before skull-pin insertion. Serum levels of TNF-α、IL-6 and IL-1β will be measured and compared at before surgery, 1h, 24h and 72h after surgery, respectively. VAS score, dosage of pain-control medicine and NRS score at the first three days after surgery, ratio of intracranial infection within 30d after surgery, and total hospitalization days and medical expenditure will also be recorded and compared between the two groups.

NCT ID: NCT02648997 Recruiting - Meningiomas Clinical Trials

An Open-Label Phase II Study of Nivolumab in Adult Participants With Progessive/ Recurrent Meningioma

Start date: March 2016
Phase: Phase 2
Study type: Interventional

This research study is studying targeted immunotherapies as a possible treatment for recurrent meningioma. The names of the study interventions involved in this study are nivolumab and ipilimumab.

NCT ID: NCT01880749 Completed - Clinical trials for Neurofibromatosis Type 2

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

Start date: June 2013
Phase: Early Phase 1
Study type: Interventional

The primary objective is to estimate the proportions of vestibular schwannomas (VS) and meningiomas after 10 days of exposure to the study drug RAD001 at a dose of 10 mg daily, as determined by immunohistochemistry. This is a "phase 0" PK (pharmacokinetic) and PD (pharmacodynamic) study of RAD001 in patients with Neurofibromatosis Type 2-related and sporadic VS and meningiomas. Enrolled patients will take RAD001 prior to a scheduled VS or meningioma surgery, and blood and tissue samples will be obtained for further analysis.

NCT ID: NCT01655927 Recruiting - Neoplasms Clinical Trials

Efficacy of Tranexamic Acid in Brain Tumor Resections

COLFIRE
Start date: July 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Tranexamic Acid is effective or not in the reduction of intraoperative bleeding loss in brain tumors resections.

NCT ID: NCT00517959 Active, not recruiting - Craniopharyngioma Clinical Trials

SCRT Versus Conventional RT in Children and Young Adults With Low Grade and Benign Brain Tumors

SCRT
Start date: May 2001
Phase: Phase 3
Study type: Interventional
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