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Optimization of Serum Phosphorus Level and Weaning From Mechanical Ventilation

Mechanical Ventilation Clinical Trial

Official title:
Impact of Serum Phosphorus Level Optimization on Weaning From Mechanical Ventilation in Adult ICU Patients

Clinical Trial Summary

The goal of this clinical trial is to test the impact of serum phosphorus level optimization on weaning from mechanical ventilation in adult ICU patients in Alexandria University Hospitals. The main questions it aims to answer are: - Does serum phosphorus level optimization affect the duration of mechanical ventilation? - Is serum phosphorus level optimization associated with successful weaning from mechanical ventilation? In critically ill patients, phosphorus supplementation is done using Sodium glycerophosphate pentahydrate solution.

Clinical Trial Description

Investigators will document patients' data in terms of independent variables and will randomly allocate the participants into one of the two study groups mentioned below. - Control group, defined by maintaining serum phosphorus level at ≥ 2.5 and < 3.5 mg/dL. - Intervention group, defined by optimization of serum phosphorus P to ≥ 3.5 and ≤ 4.5 mg/dL (Average 4mg/dL). Regression and comparative statistics will be used to determine whether the optimum serum phosphorus level offers a benefit in terms of the duration of mechanical ventilation and the success of weaning from mechanical ventilation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05682846
Study type Interventional
Source Alexandria University
Contact
Status Completed
Phase N/A
Start date May 1, 2022
Completion date February 28, 2023
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