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NCT05038111 Clinical Trial

Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery

Mechanical Ventilation Clinical Trial

Official title:
Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05038111
Other study ID # 110006-F
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 11, 2021
Est. completion date March 25, 2021

Study information
Verified date March 2021
Source Far Eastern Memorial Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The concept of enhanced recovery after surgery (ERAS) is utilizing in multiple specialties widely. Early tracheal extubation is one of the components of ERAS that enhances postoperative recovery and reduces the length of stay in intensive care unit (ICU).Dexmedetomidine is a highly selective, shorter-acting α2-adrenergic receptor agonist that has both analgesic and sedativeeffects.It was associated with decreased mortality, time to extubation, and hospital length of stay in cardiac surgical patients according to previous studies.The purpose of this study was to investigate the effect of perioperative dexmedetomidine on patients undergoing minimally invasive cardiac surgery(MICS) who were early extubated after surgery.

Recruitment information / eligibility
Status Completed
Enrollment 81
Est. completion date March 25, 2021
Est. primary completion date March 22, 2021
Accepts healthy volunteers No
Gender All
Age group 20 Years to 99 Years
Eligibility Inclusion Criteria: - Patients undergone minimal invasive off-pump coronary artery bypass graft (CABG), valvular surgery or combined procedures at Far Eastern Memorial Hospital, New Taipei City, Taiwan between January 1, 2020 and August 31, 2020. - Age above 20 y/o Exclusion Criteria: - Emergency surgery - Postoperative mechanical ventilation more than 6 hours - Extubated in the operating room

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Dexmedetomidine
perioperative dexmedetomidine infusion

Locations
Country Name City State
Taiwan Far Eastern Memorial Hospital New Taipei City

Sponsors (1)
Lead Sponsor Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Primary postoperative mechanical ventilation duration from the time the patient arrived at the ICU until extubation up to 1 week
Primary ICU and hospital length of stay through admission, up to 1 month
Secondary postoperative complications atrial fibrillation, bradyarrhythmia, myocardial infarction, cerebrovascular accident, acute renal failure and delirium according to ICD 10 on medical record, daily to discharge, up to 1 month
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