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Clinical Trial Summary

Pressure support ventilation (PSV) is the most commonly used mode in mechanical ventilated patients. Studies have shown that over-assistance was prevalent in patients undergoing PSV. Up to now, no reliable method has been recommended to select an "optimal" inspiratory support level. Pressure muscle index (PMI) was introduced recently to evaluate the degree of spontaneous breathing effort. We hypothesize that PMI might be used as an indicator for over-assistance during PSV. In this randomized crossover study, inspiratory support is set at three levels according to negative, positive and zero PMI. Inspiratory effort, work of breathing, and respiratory mechanics are compared among the three inspiratory pressure support levels.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05026463
Study type Interventional
Source Capital Medical University
Contact Jian-Xin Zhou, MD
Phone 8610 59978019
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date September 2021
Completion date February 2022

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