Inhomogeneous Ventilation in Adult Post-neurosurgical Patients

Status Recruiting

Clinical Trial Summary

Inhomogeneous ventilation was more likely to happen in patients after general anesthesia. Inhomogeneous ventilation may associate with ventilator-induced lung injury. A large number of post-neurosurgical patients was delayed extubation and received mechanical ventilation, so that, inhomogeneous ventilation was more likely to happen in the population. Electrical impedance tomography (EIT) is an noninvasive, radiation-free, high temporal resolution, relatively cheap technique in monitoring ventilation distribution bedside. The investigators aimed to investigate the incidence of inhomogeneous ventilation and factors associated with inhomogeneous ventilation in post-neurosurgical patients under mechanical ventilation.

Clinical Trial Description

Inhomogeneous ventilation was more likely to happen in patients after general anesthesia. Inhomogeneous ventilation may associate with ventilator-induced lung injury since the gravity-depend collapse and over-distention of nondependent regional in patients under mechanical ventilation. A large number of post-neurosurgical patients was delayed extubation and received mechanical ventilation, so that, inhomogeneous ventilation was more likely to happen in the population. Up to now, there is no research reported about the prevalence of inhomogeneous ventilation and the factors associated with inhomogeneous ventilation in post-neurosurgical patients, in present study, The investigators prospectively enrolled adult patients after neurosurgical operations. Electrical impedance tomography (EIT) is an noninvasive, radiation-free, high temporal resolution, relatively cheap technique in monitoring ventilation distribution bedside. The investigators aimed to investigate the incidence of inhomogeneous ventilation and factors associated with inhomogeneous ventilation in post-neurosurgical patients under mechanical ventilation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03830099
Study type	Observational
Source	Capital Medical University
Contact	Jian-Xin Zhou, MD
Phone	8610 67096579
Email	zhoujx.cn@icloud.com
Status	Recruiting
Phase
Start date	April 1, 2018
Completion date	August 31, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05921656` - Construction and Evaluation of Airway Leakage Risk Model of Patients With Endotracheal Tube
Recruiting	`NCT03941002` - Continuous Evaluation of Diaphragm Function	N/A
Withdrawn	`NCT04288076` - The Brain and Lung Interaction (BALI) Study	N/A
Completed	`NCT03031860` - Semi-quantitative Cough Strength Score (SCSS)	N/A
Completed	`NCT02545621` - A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
Completed	`NCT02312869` - Local Assessment of Management of Burn Patients	N/A
Completed	`NCT01885442` - TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients	N/A
Completed	`NCT01204281` - Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients	Phase 4
Terminated	`NCT01059929` - Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)	Phase 4
Completed	`NCT00824239` - Intermittent Sedation Versus Daily Interruption of Sedation in Mechanically Ventilated Patients	Phase 3
Completed	`NCT00529347` - Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern	Phase 1
Unknown status	`NCT00260676` - Protective Ventilatory Strategy in Potential Organ Donors	Phase 3
Terminated	`NCT00205517` - Sedation and Psychopharmacology in Critical Care	N/A
Completed	`NCT03281785` - Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients.	N/A
Recruiting	`NCT04110613` - RCT: Early Feeding After PEG Placement	N/A
Completed	`NCT04410783` - The Emergency Department Sedation Pilot Trial	N/A
Recruiting	`NCT04821453` - NAVA vs. CMV Crossover in Severe BPD	N/A
Completed	`NCT03930147` - Ventilation With ASV Mode in Children	N/A
Recruiting	`NCT05029167` - REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)	N/A
Recruiting	`NCT04849039` - Lung Microbiota and VAP Development (PULMIVAP)