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Hyperoxemia and Ventilator-associated Pneumonia — SOH-VAP  

Mechanical Ventilation Clinical Trial

Official title:
Impact of Hyperoxemia on Incidence of Ventilator-associated Pneumonia

Clinical Trial Summary

The aim of this prospective cohort single-center observational study is to determine the impact of hyperoxemia on ventilator-associated pneumonia (VAP) occurrence. - SpO2 will be continuously recorded in order to determine the percentage of time spent with hyperoxemia. - Patients with VAP will be prospectively identified. - Patient characteristics and risk factors for VAP will be prospectively collected. - Oxidant stress will be prospectively investigated in study patients: glutathion peroxidase (GPX), plasmatic superoxyde dismutase (SOD), total plasmatic antioxidant status (SAT) and urinary 8-isoprostanes will be performed at ICU admission, once a week, and at VAP occurrence. Patients with VAP will be compared with those with no VAP

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03434821
Study type Observational
Source University Hospital, Lille
Contact
Status Completed
Phase
Start date March 15, 2018
Completion date April 30, 2022
View Details
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