Cardiac, Pulmonary and Diaphragm Sonography for the Early Diagnosis of the Different Etiologies Underlying Failure of Weaning From Mechanical Ventilation

Mechanical Ventilation Clinical Trial

— WEAN US  

Official title:

Combined Cardiac, Pulmonary and Diaphragm Sonography for the Evaluation of Failure in Ventilation Weaning

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03261440
• Other study ID #: KLEIN 2016
• Status: Recruiting
• Phase: N/A
• First received: August 23, 2017
• Last updated: August 23, 2017
• Start date: November 2016
• Est. completion date: November 2017

Study information

• Verified date: August 2017
• Source: Centre Hospitalier Universitaire Dijon
• Contact: Belaïd BOUHEMAD
• Phone: 03.80.29.93.42
• Email: belaid.bouhemad[@]chu-dijon.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Weaning patients off ventilation in an ICU is sometimes difficult, because of three major inter-related etiologies: impaired lung, heart and diaphragm function. In this context, ultrasonography during tests to wean patients off ventilation could make it possible to diagnose cardiac dysfunction, a loss of pulmonary aeration or diaphragm dysfunction and thus reduce the number of failures at extubation.

The study will be carried out in 100 patients on mechanical ventilation following abdominal or heart surgery, who will have echocardiography, and pulmonary and diaphragm ultrasonography.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: November 2017
• Est. primary completion date: November 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Patients on mechanical ventilation for at least 48 hours

• Age = 60 years

• Patients who have undergone abdominal or heart surgery

Exclusion Criteria:

• Patients with a known neuromuscular disease

• Patients younger than 60 years

• Duration of mechanical ventilation <48h

• Non-surgical patients

• Patients with severe COPD

Related Conditions & MeSH terms

• Following Heart or Abdominal Surgery
• Mechanical Ventilation

Locations

Country	Name	City	State
France	CHU Dijon Bourgogne	Dijon

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire Dijon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Echocardiography		At baseline
Primary	Lung ultrasonography		At baseline
Primary	Diaphragm ultrasonography		At baseline