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Decreasing Trigger Sensitivity Could Assist PEEP to Further Improve Regional Ventilation Distribution

Mechanical Ventilation Clinical Trial

Official title:
Decreasing Trigger Sensitivity Could Assist PEEP to Further Improve Regional Aeration and Homogeneity During Pressure Assist Ventilation: A Preliminarily Physiological Study

Clinical Trial Summary

In mechanically ventilated patients during supine position, alveolar collapse usually distributes in dependent lung region.Decrease of flow trigger sensitivity might improve homogeneous of tidal volume distribution.

Clinical Trial Description

In mechanically ventilated patients during supine position, alveolar collapse usually distributes in dependent lung region. High positive end expiratory pressure (PEEP) has been applied to improve the homogeneous distribution of ventilation by increasing the end expiratory lung ventilation (EELV) and alveolar recruitment. However, for patients who increasing PEEP in some extent still existed poor aeration in the dependent region, further elevating PEEP seems to be unreasonable that perhaps lead to overdistension. Decreasing trigger sensitivity might further evoke inspiratory efforts to improve the ventilation for this type of patients.The Electrical impedance tomography (EIT) was applied in monitoring the regional ventilation distribution at the bedside. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03241654
Study type Observational
Source Capital Medical University
Contact
Status Completed
Phase N/A
Start date May 1, 2017
Completion date February 1, 2018
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