Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery

Mechanical Ventilation Clinical Trial

Official title:

Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03155555
• Other study ID #: NK/3046/MD/400
• Status: Completed
• Start date: December 2016
• Est. completion date: December 17, 2017

Study information

• Verified date: April 2019
• Source: Postgraduate Institute of Medical Education and Research
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index of fluid responsiveness in mechanically ventilated children intra-operatively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: December 17, 2017
• Est. primary completion date: December 17, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Year to 12 Years

Eligibility

Inclusion Criteria:

• Patients scheduled for mon-cardiac surgeries under general endotracheal anaesthesia in supine position with expected duration more than 1 hour

Exclusion Criteria:

• Known congenital heart disease

• Any non-sinus rhythm, arrhythmias

• Patients on vasoactive medications

• Chest wall deformities, situs non solitus (eg. dextrocardia)

• Patients scheduled for open chest surgeries

• History of neck surgery/ carotid interventions

Related Conditions & MeSH terms

• Anesthesia, Endotracheal
• Anesthesia, General
• Fluid Responsiveness
• Mechanical Ventilation

Intervention

Other:
• Measurement of aortic and carotid Doppler peak systolic velocity variation
Aortic peak systolic velocity variation to be measured by echocardiography from apical five chamber and suprasternal windows alongwith carotid peak systolic velocity variation by Doppler ultrasound simultaneously at intermittent time points intermittently.

Locations

Country	Name	City	State
India	Postgraduate Institute of Medical Education & Research	Chandigarh

Sponsors (1)

Lead Sponsor	Collaborator
Postgraduate Institute of Medical Education and Research

Country where clinical trial is conducted

India, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation	Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation by Bland-Altman analysis	Measurements made within 3 minutes
Secondary	Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows	Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows by Bland-Altman analysis	Measurements made within 3 minutes