Maximal Inspiratory Pressure at Extubation: Relationship With Mortality

Mechanical Ventilation Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02363231
• Other study ID #: 2013-A01157-38
• Status: Completed
• Phase: N/A
• First received: February 9, 2015
• Last updated: January 8, 2016
• Start date: January 2014
• Est. completion date: January 2016

Study information

• Verified date: January 2016
• Source: University Hospital, Rouen
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Agence Nationale de Sécurité du Médicament et des produits de santé
• Study type: Observational

Clinical Trial Summary

The process of weaning from mechanical ventilation was decided after clinical judgment and weaning predictive index. Nevertheless, indexes predicting weaning outcome like Maximal Inspiratory Pressure (MIP) are frequently inaccurate. However the long-term involvement of respiratory muscles in critically ill patients has not been established. The objective of this study was to assess the relationship on MIP at extubation on one-year mortality in critically ill patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 124
• Est. completion date: January 2016
• Est. primary completion date: January 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Mechanical ventilation at least at 24 hours

Exclusion Criteria:

• Delirium

• Cognitive dysfunction

• refusal to participate

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Mechanical Ventilation

Locations

Country	Name	City	State
France	Le Havre, Jacques Monod Hospital	Montivilliers

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Rouen

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality		One year after extubation	No
Secondary	Time to mechanical ventilation weaning		During Intensive care unit hospitalization	No