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NCT00432718 Clinical Trial

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

Mechanical Ventilation Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00432718
Other study ID # 342/01
Secondary ID
Status Completed
Phase N/A
First received February 7, 2007
Last updated February 7, 2007
Start date August 2001

Study information
Verified date February 2007
Source Hospital do Cancer, Sao Paulo
Contact n/a
Is FDA regulated No
Health authority Brazil: National Committee of Ethics in Research
Study type Interventional

Clinical Trial Summary

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

Recruitment information / eligibility
Status Completed
Enrollment 260
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria:

- Previous mechanical ventilation in the last month

- Mechanical ventilation for more than 6 hours before arrival at ICU,

- Contraindication to bronchoscopy and

- Be expected to die or undergo withdrawal treatment within 48 hours-

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind, Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Procedure:
• Saline Instillation before Tracheal Suctioning

Locations
Country Name City State
Brazil ICU Hospital do Câncer Sao Paulo SP

Sponsors (1)
Lead Sponsor Collaborator
Hospital do Cancer, Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome
Type Measure Description Time frame Safety issue
Primary incidence of ventilator associated pneumonia
Secondary atelectasis
Secondary tube occlusion
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