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Mechanical Ventilation clinical trials

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NCT ID: NCT00789412 Completed - Pain Clinical Trials

Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients

Start date: August 2008
Phase: N/A
Study type: Observational

The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the quality of analgosedation in noncommunicative intensive care unit patients?

NCT ID: NCT00787098 Completed - Clinical trials for Mechanical Ventilation

Investigating Modes of Progressive Mobility

Start date: November 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the effects of specific activities with and without an early therapeutic mobility (ETM) protocol among patients who experience three or more days of mechanical ventilation. A second purpose is to examine staff/delivery system and patient factors that influence the initiation and progression of activity with and without an ETM protocol. The hypothesis is that ETM protocols will result in improved patient outcomes.

NCT ID: NCT00702169 Completed - Clinical trials for Mechanical Ventilation

Continuous Monitoring of the Lungs Ventilation Dynamics During Mechanical Ventilation

Start date: December 2007
Phase:
Study type: Observational

Background: Patients that suffer from respiratory failure and need mechanical ventilation are at risk of further deterioration due to complications induced by progression of lung disease or the mechanical ventilation. The complications usually develop in a progressive manner, but are currently detected relatively late, when there is already severe and life threatening deterioration in patient oxygenation and sometimes irreversible damages. Objective:To measure chest wall dynamics, derived from sensors placed on the chest and abdomen. Methods: The system comprises of patches attached to the chest wall and upper abdomen that include mechanical sensors that measure the mechanics of lung inflation and deflation.

NCT ID: NCT00557999 Completed - Clinical trials for Mechanical Ventilation

Mechanical Ventilation Weaning Protocol in the Coronary Care Unit

Start date: March 2006
Phase: N/A
Study type: Interventional

The following objectives were used for comparison: 1) primary objective: reintubation rate during hospitalization; 2) secondary objectives: length of hospitalization at the Coronary Care Unit; time from intubation to start of weaning; time from start of weaning to extubation; time from SBT and extubation; presence of respiratory infection in patients requiring reintubation; mortality of patients requiring reintubation.

NCT ID: NCT00529347 Completed - Clinical trials for Mechanical Ventilation

Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern

Start date: September 2007
Phase: Phase 1
Study type: Interventional

Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assist to spontaneous breathing based on the detection of the electrical activity of the diaphragm. We study the effect of changing ventilatory parameters on the patient's breathing pattern during NAVA.

NCT ID: NCT00475579 Completed - Clinical trials for Mechanical Ventilation

Endotracheal Tube With Polyurethane Cuff and Subglottic Secretion Drainage

A/N
Start date: March 2006
Phase: Phase 4
Study type: Interventional

Patients mechanically ventilated using an endotracheal tube with a subglottic secretion drainage lumen and a polyurethane cuff may develop lower ventilator-associated pneumonia than using a conventional endotracheal tube

NCT ID: NCT00460252 Completed - Hyperglycemia Clinical Trials

Tight Glycemic Control by eMPC Algorithm in Medical ICU Patients.

Start date: May 2006
Phase: N/A
Study type: Interventional

This is an open mono-centre randomised controlled trial performed at the Medical University Graz including a treatment visit (V1). In the treatment visit (V1) after admittance to the ICU arterial blood glucose values will be monitored and either the software-algorithm eMPC will be used to adjust the infusion rate of intravenously administered human soluble insulin to normalise arterial blood glucose or routine treatment will be used to establish tight glycaemic control. The treatment visit will last for 72 hours. The primary hypothesis of the study is that blood glucose control by the eMPC algorithm is not inferior compared to the implemented routine protocol.

NCT ID: NCT00448565 Completed - Respiratory Failure Clinical Trials

Prediction of Extubation Success by the Patient

Start date: January 2007
Phase: N/A
Study type: Observational

The evidence-based approach to wean and consecutively extubate patients is based solely on objective criteria/tests. The introduction of subjective criteria could further improve the actual method.

NCT ID: NCT00432718 Completed - Clinical trials for Mechanical Ventilation

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

Start date: August 2001
Phase: N/A
Study type: Interventional

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

NCT ID: NCT00419601 Completed - Clinical trials for Mechanical Ventilation

Rapip Study: Clinical Trial on Remifentanyl for Analgesia and Sedation of Ventilated Neonates and Infants

Start date: November 2006
Phase: Phase 3
Study type: Interventional

It shall be investigated whether ventilated neonates and infants with a remifentanyl based analgesia and sedation can be extubated faster after discontinuation of the opioid infusion compared to neonates and infants with a fentanyl based analgesia and sedation.