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Clinical Trial Summary

This is a multi-part, randomized, double-blind, placebo-controlled Phase 2 clinical study comparing the safety and efficacy of CGT9486 plus best supportive care (BSC) with placebo plus BSC in patients with nonadvanced systemic mastocytosis (NonAdvSM), including indolent systemic mastocytosis and smoldering systemic mastocytosis, whose symptoms are not adequately controlled by BSC. This study will be conducted in three parts. Patients in Parts 1 and 2 will receive CGT9486 or placebo, and may roll over onto Part 3 to receive treatment with CGT9486.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05186753
Study type Interventional
Source Cogent Biosciences, Inc.
Contact Hina Jolin, PharmD
Phone +1 (617) 945-5576
Email [email protected]
Status Recruiting
Phase Phase 2
Start date January 2022
Completion date November 2026

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