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SSM clinical trials

View clinical trials related to SSM.

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NCT ID: NCT05186753 Recruiting - Mastocytosis Clinical Trials

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Start date: June 27, 2022
Phase: Phase 2
Study type: Interventional

This is a multi-part, randomized, double-blind, placebo-controlled Phase 2 clinical study comparing the safety and efficacy of bezuclastinib (CGT9486) plus best supportive care (BSC) with placebo plus BSC in patients with nonadvanced systemic mastocytosis (NonAdvSM), including indolent systemic mastocytosis and smoldering systemic mastocytosis, whose symptoms are not adequately controlled by BSC. This study will be conducted in three parts. Patients in Parts 1a, 1b and 2 will receive bezuclastinib or placebo, and may roll over onto Part 3 to receive treatment with bezuclastinib.

NCT ID: NCT04475237 Completed - Mandibular Diseases Clinical Trials

Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model

Start date: January 1, 2020
Phase:
Study type: Observational

Hundred already taken CT-scans (50 male and 50 female) will be anonymized. These scans will be segmented and implemented into a statistical shape model that will be used to predict missing hard tissue of a mandible based on the remaining bone.