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Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Mastocytosis Clinical Trial

Official title:
Phase IIa, Open-label, Randomized Study of Oral AB1010 in Patients With Systemic Indolent Mastocytosis With Handicap and Not Bearing Activating Point Mutations in the Phosphotransferase Domain of c-Kit Such as the Main Mutation Asp-816-Val (D816V)

Clinical Trial Summary

This is a 12 weeks study aimed at assessing the safety and efficacy of 2 doses of AB1010 in patients suffering from indolent systemic mastocytosis with handicap.

Clinical Trial Description

Efficacy will be assessed based on:

Pruritus score Number of flush per day Pollakyuria (on a daily basis) Number of stools per day QLQ-C30 score Hamilton Rating Scale for depression ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00831974
Study type Interventional
Source AB Science
Contact
Status Completed
Phase Phase 2
Start date October 2004
View Details
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