Clinical Trials Logo
  1. Home
  2. Marfan Syndrome
  3. NCT05578469
  4. Details
NCT05578469 Clinical Trial

Surgical Treatment of Marfan Syndrome With Subluxation Lens

Marfan Syndrome Clinical Trial

Official title:
Effect of Different Surgical Treatment of Marfan Syndrome With Subluxation Lens

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05578469
Other study ID # 2022-0765
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date January 1, 2016
Est. completion date December 30, 2024

Study information
Verified date September 2022
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To analyze the postoperative visual effects, and to compare the safety and efficacy of different surgical treatment with of Marfan Syndrome with subluxation lens.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 50
Est. completion date December 30, 2024
Est. primary completion date November 1, 2022
Accepts healthy volunteers No
Gender All
Age group 8 Years to 55 Years
Eligibility Inclusion Criteria: 1. Patients diagnosed with MFS according to the revised Ghent etiology. 2. refractive errors difficult to correct. 3. pupillary block glaucoma caused by severe dislocation of the lens Exclusion Criteria: Keratoconus, late glaucoma, uveitis, history of traumatic lens dislocation, and preoperative retinal rupture with or without retinal detachment (RD)

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• surgical treatment of Marfan Syndrome with subluxation lens
different surgical treatment of Marfan Syndrome with subluxation lens

Locations
Country Name City State
China Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou

Sponsors (1)
Lead Sponsor Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Uncorrected distance visual acuity 1 month postoperatively
Primary Uncorrected distance visual acuity 3 month postoperatively
Primary Corrected distance visual acuity 1 month postoperatively
Primary Corrected distance visual acuity 3 month postoperatively
Primary intraocular pressure 1 month postoperatively
Primary intraocular pressure 3 month postoperatively
Primary postoperative complication Early and late stages
Secondary Postoperative astigmatism and astigmatism axial of cornea 1 month postoperatively
Secondary Postoperative astigmatism and astigmatism axial of cornea 3 month postoperatively
Secondary endothelial cell count 1 month postoperatively
Secondary endothelial cell count 3 month postoperatively
See also
  Status Clinical Trial Phase
Terminated NCT00763893 - Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome Phase 3
Recruiting NCT05809323 - Marfan Syndrome Moderate Exercise Trial II N/A
Completed NCT04776668 - Living With Marfan Syndrome and Your Aorta
Recruiting NCT01949233 - The Oxford Marfan Trial Phase 2
Active, not recruiting NCT01145612 - Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome Phase 3
Completed NCT00723801 - Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome Phase 3
Completed NCT04641325 - Marfan Syndrome Moderate Exercise Pilot N/A
Recruiting NCT06257004 - Genome-wide Epistasis for Cardiovascular Severity in Marfan Study
Completed NCT01322165 - National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions N/A
Recruiting NCT05700175 - Transcriptomic Study of Adult Population With Marfan Syndrome
Completed NCT00782327 - Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers Phase 3
Not yet recruiting NCT05838235 - Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome N/A
Recruiting NCT02148900 - Development of a Blood Test for Marfan Syndrome N/A
Active, not recruiting NCT05980104 - Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions N/A
Recruiting NCT02050113 - Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices N/A
Completed NCT00001641 - Study of Heritable Connective Tissue Disorders N/A
Completed NCT01715207 - Comparison Study of the Effect of Aliskiren Versus Negative Controls on Aortic Stiffness in Patients With Marfan Syndrome Under Treatment With Atenolol Phase 3
Completed NCT05516043 - Safety and Performance of POLYTHESE® Vascular Prosthesis
Recruiting NCT04776681 - Living With Marfans and Your Aorta: Surgical Outcomes Study
Completed NCT03236571 - Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome. N/A