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National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions — GenTAC  

Turner Syndrome Clinical Trial

Official title:
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

Clinical Trial Summary

The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) was initiated in 2006 by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). GenTAC established a registry of 3706 patients with genetic conditions that may be related to thoracic aortic aneurysms and collected medical data and biologic samples. The study ended in September 2016. Data and samples are available from NHLBI and requests should be made to BioLINCC. See the NHLBI website for more information: https://www.nhlbi.nih.gov/research/resources/gentac/.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

  • Aneurysm
  • Aortic Aneurysm
  • Aortic Aneurysm, Thoracic
  • Aortic Coarctation
  • Aortic Valve Stenosis
  • Bicuspid Aortic Valve With Coarctation
  • Bicuspid Aortic Valve With Family History
  • Bicuspid Aortic Valve Without Known Family History
  • Craniosynostoses
  • Ehlers-Danlos Syndrome
  • Familial Thoracic Aortic Aneurysm and Dissections
  • FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation
  • Gonadal Dysgenesis
  • Heart Defects, Congenital
  • Heart Diseases
  • Heart Valve Diseases
  • Loeys-Dietz Syndrome
  • Marfan Syndrome
  • Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo
  • Other Congenital Heart Disease
  • Primary Ovarian Insufficiency
  • Shprintzen-Goldberg Syndrome
  • Syndrome
  • Turner Syndrome
Clinical Trial Details
NCT number NCT01322165
Study type Observational
Source National Heart, Lung, and Blood Institute (NHLBI)
Contact
Status Completed
Phase N/A
Start date November 2007
Completion date September 2016
View Details
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