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Malocclusion clinical trials

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NCT ID: NCT04825951 Completed - Clinical trials for Malocclusion, Angle Class III

Dentofacial Effects Of Two Non-Compliance Appliances In The Treatment Of Growing Skeletal Class III Patients

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Early orthodontic treatment of Class III malocclusions with skeletal and dentoalveolar imbalances, represents a continuous dilemma. This difficulty starts from their meticulous diagnosis and treatment planning till reaching satisfactory results and finally stability. Some appliances could be used to correct growing skeletal Class III patients, improving the skeletal and dentoalveolar relationships, creating proper conditions for final orthodontic treatment, more importantly avoiding surgery. These appliances remove patient compliance from the equation.

NCT ID: NCT04823325 Completed - Clinical trials for Class III Malocclusion

Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers

RAP
Start date: January 5, 2019
Phase:
Study type: Observational

A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular incisor root resorption.

NCT ID: NCT04815564 Recruiting - Clinical trials for Osteogenesis Imperfecta

Clear Aligners for the Treatment of Dental Malocclusion in OI

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Misalignment of teeth and jaws (also called malocclusion) is a common life altering problem facing many individuals with Osteogenesis Imperfecta (OI). The presence of Dentinogenesis Imperfecta in teeth of OI individuals makes the use of conventional orthodontics in the form of braces very challenging. Clear aligners are newer form of orthodontic treatment and is less invasive than braces. Therefore, the aim of our study is to evaluate the efficiency and safety of using Invisalign clear aligners for orthodontic treatment in individuals with Osteogenesis Imperfecta. We seek individual with Osteogenesis Imperfecta, with mild to moderate malocclusion and no prior history of orthodontic treatment. This study will be held at three sites - McGill University, University of California Los Angeles and National Institute of Dental and Craniofacial research. This study will for the first time, help define guidelines for safe and efficient orthodontic treatment using clear aligners in individuals with Osteogenesis Imperfecta. If successful, this approach can rapidly be implemented into clinical practice, as the Invisalign system is readily available to orthodontists.

NCT ID: NCT04814173 Completed - Malocclusion Clinical Trials

The Efficacy of Tow Mechanics for Total-maxillary-arch-distalization

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

Patients with class II division 1 malocclusion who have increased overjet will be treated in this study. The efficacy of one-jaw and tow-jaw mechanics for mini-implants anchored total-maxillary-arch-distalization in the treatment of class II division 1 malocclusion will be assessed. The skeletal, dental and soft tissues changes resulted by these tow interventions will be studied. As well as, the pain levels, oral-health related quality of life during all stages of the treatment and the smile components will be explored and compared with the traditional treatment results of this type of malocclusion (en-mass retraction with first premolars extraction). There are three groups : 1. a group of patients in which participants will be undergo to the one-jaw mechanic for mini-implants anchored total-maxillary-arch-distalization (mini-implants in the maxillary arch). 2. a group of patients in which participants will be undergo to the tow-jaw mechanic for mini-implants anchored total-maxillary-arch-distalization (mini-implants in the mandibular arch with class II elastics). 3. a group of patients in which participants will be undergo to the en-mass retraction with first premolars extraction with mini-implants in the maxillary arch.

NCT ID: NCT04810286 Recruiting - Clinical trials for Class II Division 1 Malocclusion

Prefabricated Versus 3D-Printing Myofunctional Appliances

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The aim of this clinical study is to evaluate the dentoskeletal effects of Class II division 1 treatment in growing patients with a prefabricated myofunctional appliance versus a 3D-printing myofunctional appliance.

NCT ID: NCT04756843 Recruiting - Dental Crowding Clinical Trials

Early Orthodontic Treatment of Dental Crowding

Start date: November 18, 2022
Phase: N/A
Study type: Interventional

Aim of the study is to compare treatment duration and effects of orthodontic treatment of dental crowding between treatments started at different stages of mixed dentition phase. The randomized controlled trial study will be conducted in a public health care center.

NCT ID: NCT04744337 Completed - Clinical trials for Class II Division 2 Malocclusion

TMJ Adaptations by Orthodontic Treatment in Adolescent Females With Angle's Class II Division 2 Malocclusion: MRI Study

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to document the changes brought about in the internal anatomic relationships of the TMJ complex,positional changes of glenoid fossa with respect to adjacent cranial structures after completion of fixed orthodontic treatment in adolescent females initially treated with removable functional appliances for skeletal class II, Angle's class II division 2 Malocclusion.

NCT ID: NCT04743700 Recruiting - Clinical trials for Angle Class II, Division 1 Malocclusion

"Effects of Piezocision vs Micro-osteoperforations on the Rate of Maxillary Canine Retraction

Start date: December 25, 2020
Phase: N/A
Study type: Interventional

Acceleration of orthodontic tooth movement persuades tremendous rise in the interest of adolescents and aduts, as it not only shortens the treatment duration but also lessens the incidence of white spot lesions, root resorption, periodontal and other soft tissue problems. Minimal invasive techniques i.e.both piezocision and micro-osteoperforations had promising results in accelerating tooth movement. Therefore current study will provide evidence for better minimal invasive technique in terms of reducing treatment time and patient comfort.

NCT ID: NCT04743258 Recruiting - Clinical trials for Class II Division 1 Malocclusion

Bilateral Premolar Extraction vs Distalization: A Randomised Clinical Trial

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable. Treatment of class II malocclusion due to maxillary protrusion can be done with bilateral maxillary first premolar extraction followed by en-masse retraction of upper anterior teeth using mini implants placed between maxillary 2nd premolar & 1st molar. Treatment of class II malocclusion due to maxillary protrusion without premolar extraction frequently requires distalization of maxillary molars into Class I molar relation by means of extra-oral or intraoral forces. Absolute skeletal anchorage, available 24 hours a day is an alternative method for molar distalization. Zygomatic miniplates fixed at a distance from the root apices, allows distalization of entire dentition as there is no interference between the fixation device and roots of the teeth. Aims and Objectives: To evaluate dental, skeletal & soft tissue changes achieved with maxillary premolar extraction vs full arch distalization. Method of study: Patients will be allocated randomly to 2 groups-G1 and G2. Patients in G1 will undergo bilateral maxillary 1st premolar extraction before bonding followed by leveling & alignment. Maxillary arch will be stabilized with the help of 0.019"×0.025" stainless steel wire. Hooks will be soldered on archwire used for stabilizing dentition. Mini implants will be placed under local anaesthesia between maxillary 2nd premolar & 1st molar. Ni-Ti closed coil spring will be used to apply a force for en masse retraction of maxillary anterior teeth . In G2, treatment will be initiated by bonding 0.022" slot MBT preadjusted edgewise appliance. Maxillary arch will be stabilized with the help of 0.019"×0.025" stainless steel wire. Zygomatic miniplates will be placed bilaterally. Hooks will be soldered on archwire used for stabilizing dentition. Ni-Ti closed coil spring will be used to apply a force .

NCT ID: NCT04713280 Completed - Dental Malocclusion Clinical Trials

Maxillary Versus Bi-Maxillary Posterior Segments Intrusion Adult Subjects With Skeletal Open Bite

Start date: September 17, 2020
Phase: N/A
Study type: Interventional

Compare between bi-maxillary (maxillary and mandibular) posterior dento-alveolar intrusion and maxillary posterior dento-alveolar intrusion as regards open bite closure.